ACVR2A antibody (AA 20-140)

Catalog No. ABIN3015792

This Rabbit Polyclonal antibody specifically detects ACVR2A in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for ACVR2A antibody (AA 20-140) (ABIN3015792)

Target: ACVR2A (Activin A Receptor, Type IIA (ACVR2A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACVR2A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ACVR2A Antibody

Binding Specificity: AA 20-140

Sequence: AILGRSETQE CLFFNANWEK DRTNQTGVEP CYGDKDKRRH CFATWKNISG SIEIVKQGCW LDDINCYDRT DCVEKKDSPE VYFCCCEGNM CNEKFSYFPE MEVTQPTSNP VTPKPPYYNI L

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-140 of human ACVR2A (NP_001607.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ACVR2A

Target: ACVR2A (Activin A Receptor, Type IIA (ACVR2A))

Alternative Name: ACVR2A

Background: This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene.,ACVR2A,ACTRII,ACVR2,Cancer,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Endocrine & Metabolism,Amino acid metabolism,Stem Cells,ACVR2A

Molecular Weight: 45 kDa/57 kDa

Gene ID: 92

UniProt: P27037