Lemur tyrosine Kinase 2 (LMTK2) (N-Term), (AA 70-100) antibody

Details for Product No. ABIN391208
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Antigen
Synonyms AATYK2, BREK, KPI-2, KPI2, LMR2, cprk, 2900041G10Rik, A330101P12Rik, aatyk2
Epitope
N-Term, AA 70-100
(10), (5), (2), (1), (1)
Reactivity
Human
(32), (1), (1), (1)
Host
Rabbit
(21), (7), (3)
Clonality (Clone)
Polyclonal ()
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(27), (26), (10), (10), (10), (4), (2), (1)
Pubmed 3 references available
Catalog no. ABIN391208
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This LMTK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-100 AA from the N-terminal region of human LMTK2.
Clone RB8233
Isotype Ig
Specificity This LMTK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78~107 amino acids from the N-terminal region of human LMTK2.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name LMTK2
Background Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).
Synonyms: KPI-2 protein, LMTK2,
Molecular Weight 164927 DA
Gene ID 22853
UniProt Q8IWU2
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Cycle, Transcription Factors, Signaling, Metabolism, Cell Structure
Application Notes WB = 1:1000, IHC = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Lemur tyrosine Kinase 2 (LMTK2) (N-Term), (AA 70-100) antibody Western blot analysis of LTK2 N-term (ABIN391208) in Hela cell line lysates (35 µg/lane). LTK2 (arrow) was detected using the purified polyclonal antibody.
anti-Lemur tyrosine Kinase 2 (LMTK2) (N-Term), (AA 70-100) antibody (2) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma
Background publications Wang, Brautigan: "A novel transmembrane Ser/Thr kinase complexes with protein phosphatase-1 and inhibitor-2." in: The Journal of biological chemistry, Vol. 277, Issue 51, pp. 49605-12, 2002 (PubMed).

Scherer, Cheung, MacDonald et al.: "Human chromosome 7: DNA sequence and biology...." in: Science (New York, N.Y.), Vol. 300, Issue 5620, pp. 767-72, 2003 (PubMed).

Kesavapany, Lau, Ackerley et al.: "Identification of a novel, membrane-associated neuronal kinase, cyclin-dependent kinase 5/p35-regulated kinase." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 23, Issue 12, pp. 4975-83, 2003 (PubMed).

Hosts (21), (7), (3)
Reactivities (32), (1), (1), (1)
Applications (27), (26), (10), (10), (10), (4), (2), (1)
Epitopes (10), (5), (2), (1), (1)
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