NUAK Family, SNF1-Like Kinase, 2 (NUAK2) (N-Term), (AA 67-96) antibody

Details for Product No. ABIN391234
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Antigen
Epitope
N-Term, AA 67-96
(8), (2), (1), (1)
Reactivity
Human
(40), (19), (18), (12), (12)
Host
Rabbit
(36), (4)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(31), (18), (10), (6), (4), (3), (2)
Pubmed 1 reference available
Quantity 400 µL
Options
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Catalog No. ABIN391234
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Immunogen This NUAK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 AA from the N-terminal region of human NUAK2.
Clone RB8576
Isotype Ig
Specificity This NUAK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74~104 amino acids from the N-terminal region of human NUAK2.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name NUAK2
Background Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells.
Synonyms: NUAK family SNF1-like kinase 2, SNF1/AMP kinase-related kinase, SNARK, NUAK2,
Molecular Weight 69612 DA
Gene ID 81788
UniProt Q9H093
Research Area Apoptosis/Necrosis, Phospho-specific antibodies, Protein Modifications, Cancer, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-NUAK Family, SNF1-Like Kinase, 2 (NUAK2) (N-Term), (AA 67-96) antibody Western blot analysis of NUAK2 (arrow) using rabbit polyclonal NUAK2 Antibody (N-term) (ABIN391234). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the NUAK2 gene (Lane 2) (Origene Technologies).
Background publications Lefebvre, Bai, Shahmolky et al.: "Identification and characterization of a novel sucrose-non-fermenting protein kinase/AMP-activated protein kinase-related protein kinase, SNARK." in: The Biochemical journal, Vol. 355, Issue Pt 2, pp. 297-305, 2001 (PubMed).

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