NUAK2 antibody

Catalog No. ABIN7116942

The Rabbit Polyclonal anti-NUAK2 antibody (ABIN7116942) specifically detects NUAK2 in WB, ELISA, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for NUAK2 antibody (ABIN7116942)

Target: NUAK2 (NUAK Family, SNF1-Like Kinase, 2 (NUAK2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUAK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-NUAK2 Antibody

Purpose: NUAK2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: NUAK family, SNF1-like kinase, 2

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for NUAK2

Target: NUAK2 (NUAK Family, SNF1-Like Kinase, 2 (NUAK2))

Alternative Name: NUAK2

Background:

Synonyms: NUAK family SNF1-like kinase 2|Omphalocele kinase 2|SNF1/AMP kinase-related kinase (SNARK)|NUAK2|OMPHK2|SNARK

Background: Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1.

Molecular Weight: 70 kDa

Gene ID: 81788

UniProt: Q9H093