Amyloid beta Precursor Protein (Cytoplasmic Tail) Binding Protein 2 (APPBP2) (AA 242-271), (Center) antibody

Details for Product No. ABIN391423
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Antigen
Synonyms zgc:76971, wu:fb78e11, wu:fc25c09, APPBP2, DKFZp459F0530, HS.84084, PAT1, 1300003O07Rik, AI465480, Dct1, LYAAT1, TRAMD3
Epitope
AA 242-271, Center
(16), (9), (7), (3), (2), (2), (2), (2), (1), (1)
Reactivity
Human
(60), (22), (22), (13), (13), (12), (1), (1), (1), (1)
Host
Rabbit
(56), (4)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(42), (35), (12), (10), (5), (2), (2), (2), (1)
Pubmed 1 reference available
Quantity 400 μL
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Catalog No. ABIN391423
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Immunogen This PAT1(APPBP2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-271 AA from the Central region of human PAT1(APPBP2).
Clone RB8985
Isotype Ig
Specificity This PAT1(APPBP2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249~279 amino acids from the Center region of human PAT1.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein G column, followed by dialysis against PBS.
Alternative Name PAT1 (APPBP2)
Background APPBP2 interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This protein has been found to be highly expressed in breast cancer.
Synonyms: Amyloid protein-binding protein 2, Amyloid beta precursor protein-binding protein 2, APP-BP2, Protein interacting with APP tail 1, APPBP2, KIAA0228, PAT1
Molecular Weight 66722 DA
Gene ID 10513
NCBI Accession NP_006371
Research Area Cell Signaling, Cell Structure, Neurology
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 1.85 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Amyloid beta Precursor Protein (Cytoplasmic Tail) Binding Protein 2 (APPBP2) (AA 242-271), (Center) antibody Western blot analysis of anti-PAT1 (APPBP2) Antibody (Center) (ABIN391423) in HL60 cell line lysates (35 µg/lane). PAT1(arrow) was detected using the purified polyclonal antibody (1:60 dilution).
Background publications Zheng, Eastman, Vande Pol et al.: "PAT1, a microtubule-interacting protein, recognizes the basolateral sorting signal of amyloid precursor protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 25, pp. 14745-50, 1999 (PubMed).

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