Sestrin 1 (SESN1) (C-Term), (AA 312-341) antibody

Details for Product No. ABIN391992
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms zgc:91970, sestrin-1, SESN1, XPA26, pa26, sest1, PA26, SEST1, 1110002G11Rik, AU044290, Pa26, Sest1, sesn1-A
Epitope
C-Term, AA 312-341
(5), (4), (3), (3), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(39), (28), (19), (12), (12)
Host
Rabbit
(41), (2)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Flow Cytometry (FACS)
(31), (12), (10), (8), (4), (3), (2), (2), (1)
Pubmed 3 references available
Quantity 400 μL
Options
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN391992
291.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This Sestrin-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 312-341 AA from the C-terminal region of human Sestrin-1.
Clone RB18601
Isotype Ig
Specificity This Sestrin-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 319~349 amino acids from the C-terminal region of human Sestrin-1.
Predicted Reactivity Monkey,Xenopus laevis
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name Sestrin-1
Background Sestrin-1 is involved in the reduction of peroxiredoxins. This protein may also be regulator of cellular growth.
Synonyms: Sestrin-1, p53-regulated protein PA26, SEST1, PA26, SESN1
Molecular Weight 56557 DA
Gene ID 27244
UniProt Q9Y6P5
Research Area Cell Cycle, Cell Structure
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Sestrin 1 (SESN1) (C-Term), (AA 312-341) antibody Western blot analysis of Sestrin-1 antibody (C-term) (ABIN391992) in mouse heart tissue lysates (35 µg/lane). Sestrin-1 (arrow) was detected using the purified polyclonal antibody.
anti-Sestrin 1 (SESN1) (C-Term), (AA 312-341) antibody (2) Sestrin-1 Antibody (C-term) (ABIN391992) western blot analysis in NCI-H460,HL-60 cell line lysates (35 µg/lane).This demonstrates the Sestrin-1 antibody detected the Sestrin-1 protein (arrow).
anti-Sestrin 1 (SESN1) (C-Term), (AA 312-341) antibody (3) Sestrin-1 Antibody (C-term) (ABIN391992) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications Velasco-Miguel, Buckbinder, Jean et al.: "PA26, a novel target of the p53 tumor suppressor and member of the GADD family of DNA damage and growth arrest inducible genes." in: Oncogene, Vol. 18, Issue 1, pp. 127-37, 1999 (PubMed).

Peeters, Debeer, Bairoch et al.: "PA26 is a candidate gene for heterotaxia in humans: identification of a novel PA26-related gene family in human and mouse." in: Human genetics, Vol. 112, Issue 5-6, pp. 573-80, 2003 (PubMed).

Budanov, Sablina, Feinstein et al.: "Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD." in: Science (New York, N.Y.), Vol. 304, Issue 5670, pp. 596-600, 2004 (PubMed).

Validation Images
Did you look for something else?
back to top