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Details for Product No. ABIN391992

Sestrin 1 (SESN1) (C-Term), (AA 312-341) antibody

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Antigen
Synonyms PA26, SEST1, 1110002G11Rik, AU044290, Pa26, Sest1, sesn1-A, zgc:91970, sestrin-1, SESN1, XPA26, pa26, sest1
Epitope
»Alternatives C-Term, AA 312-341
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Flow Cytometry (FACS)
Pubmed 3 references available
Catalog no. ABIN391992
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This Sestrin-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 312-341 AA from the C-terminal region of human Sestrin-1.
Clone RB18601
Isotype Ig
Specificity This Sestrin-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 319~349 amino acids from the C-terminal region of human Sestrin-1.
Predicted Reactivity Monkey,Xenopus laevis
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name Sestrin-1
Background Sestrin-1 is involved in the reduction of peroxiredoxins. This protein may also be regulator of cellular growth.
Synonyms: Sestrin-1, p53-regulated protein PA26, SEST1, PA26, SESN1
Molecular Weight 56557 DA
Gene ID 27244
UniProt Q9Y6P5
Research Area Cell Cycle, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Velasco-Miguel, Buckbinder, Jean et al.: "PA26, a novel target of the p53 tumor suppressor and member of the GADD family of DNA damage and growth arrest inducible genes." in: Oncogene, Vol. 18, Issue 1, pp. 127-37, 1999 (PubMed).

Peeters, Debeer, Bairoch et al.: "PA26 is a candidate gene for heterotaxia in humans: identification of a novel PA26-related gene family in human and mouse." in: Human genetics, Vol. 112, Issue 5-6, pp. 573-80, 2003 (PubMed).

Budanov, Sablina, Feinstein et al.: "Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD." in: Science (New York, N.Y.), Vol. 304, Issue 5670, pp. 596-600, 2004 (PubMed).

Alternatives for antigen "Sestrin 1 (SESN1)", type "Antibodies"
Hosts (35), (2)
Reactivities (32), (26), (18), (14), (13), (1), (1), (1)
Applications (25), (13), (10), (5), (5), (2), (2), (1)
Conjugates (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1)
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