Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) (N-Term), (AA 32-62) antibody

Details for Product No. ABIN392042
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Antigen
Synonyms ROR1, 9530021D13Rik, Nr1f1, ROR2, ROR3, nmf267, sg, staggerer, tmgc26, NTRKR1, dJ537F10.1, 2810404D04Rik, Ntrkr1, mRor1, RGD1559469
Epitope
N-Term, AA 32-62
(12), (7), (6), (3), (3), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(53), (7), (6)
Host
Rabbit
(35), (15), (4)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(3), (2), (2), (1), (1), (1), (1)
Application
Western Blotting (WB), Flow Cytometry (FACS)
(48), (38), (13), (10), (9), (7), (5), (2)
Pubmed 2 references available
Quantity 400 μL
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Catalog No. ABIN392042
291.50 $
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Immunogen This ROR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-62 AA from the N-terminal region of human ROR1.
Clone RB1505-1506
Isotype Ig
Specificity This ROR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40~69 amino acids from the N-terminal region of human ROR1.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name ROR1
Background ROR1 is a receptor protein tyrosine kinase whose cellular role has not been determined. It is a type I membrane protein and belongs to the ROR subfamily of cell surface receptors. Studies of a similar protein in mouse suggest that this protein may interact with another receptor protein tyrosine kinase and may be involved in skeletal and cardiac development.
Synonyms: Tyrosine-protein kinase transmembrane receptor ROR1, Neurotrophic tyrosine kinase, receptor-related 1 NTRKR1
Molecular Weight 104312 DA
Gene ID 4919
UniProt Q01973
Research Area Phospho-specific antibodies, Stem Cells, Cell Signaling, Protein Modifications, Cell Structure
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) (N-Term), (AA 32-62) antibody Western blot analysis of ROR1 (arrow) using rabbit polyclonal ROR1 Antibody (N-term) (ABIN392042). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the ROR1 gene (Lane 2) (Origene Technologies).
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) (N-Term), (AA 32-62) antibody (2) Flow cytometric analysis of NCI-H460 cells using ROR1 Antibody (N-term) (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications Masiakowski, Carroll: "A novel family of cell surface receptors with tyrosine kinase-like domain." in: The Journal of biological chemistry, Vol. 267, Issue 36, pp. 26181-90, 1993 (PubMed).

Reddy, Phatak, Pleasure: "Human neural tissues express a truncated Ror1 receptor tyrosine kinase, lacking both extracellular and transmembrane domains." in: Oncogene, Vol. 13, Issue 7, pp. 1555-9, 1996 (PubMed).

Validation Images
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