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Details for Product No. ABIN392278

Testis-Specific Kinase 2 (TESK2) (AA 210-240), (Center), (Cys225) antibody

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Synonyms TESK2
»Alternatives AA 210-240, Center, Cys225
»Alternatives Human
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
»Alternatives Un-conjugated
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN392278
Quantity 400 µL
291.50 $   Plus shipping costs $45.00
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Immunogen This TESK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-240 AA from the Central region of human TESK2.
Clone RB12617
Isotype Ig
Specificity This TESK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218~247 amino acids from the Center(C225) region of human TESK2.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name TESK2
Background TESK2 is a dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. TESK2 phosphorylates cofilin at Ser-3. It may play an important role in spermatogenesis. This nuclear enzyme is thought to be activated by autophosphorylation on Ser-219. Expression is predominantly in testis and prostate, with highest concentrations in nongerminal Sertoli cells.
Synonyms: Testicular protein kinase 2
Molecular Weight 63509 DA
Gene ID 10420
UniProt Q96S53
Research Area Apoptosis/Necrosis, Protein Modifications, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Røsok, Pedeutour, Ree et al.: "Identification and characterization of TESK2, a novel member of the LIMK/TESK family of protein kinases, predominantly expressed in testis." in: Genomics, Vol. 61, Issue 1, pp. 44-54, 1999 (PubMed).

Toshima, Toshima, Takeuchi et al.: "Cofilin phosphorylation and actin reorganization activities of testicular protein kinase 2 and its predominant expression in testicular Sertoli cells." in: The Journal of biological chemistry, Vol. 276, Issue 33, pp. 31449-58, 2001 (PubMed).

Alternatives for antigen "Testis-Specific Kinase 2 (TESK2)", type "Antibodies"
Hosts (34), (13)
Reactivities (47), (23), (22), (12)
Applications (37), (25), (10), (10), (10), (2), (2), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (8), (6), (2), (2), (1), (1), (1), (1)