TESK2 antibody (Middle Region)

Catalog No. ABIN360162

Product Details anti-TESK2 Antibody

Target: TESK2 (Testis-Specific Kinase 2 (TESK2))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TESK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to TESK2.

Purification: Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center(C225) region of human TESK2.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for TESK2

Target: TESK2 (Testis-Specific Kinase 2 (TESK2))

Alternative Name: TESK2 (TESK2 Products)

Synonyms: TESK2 antibody, testis-specific kinase 2 antibody, dual specificity testis-specific protein kinase 2 antibody, TESK2 antibody, LOC100548964 antibody, tesk2 antibody, Tesk2 antibody

Background: TESK2 is a dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. TESK2 phosphorylates cofilin at Ser-3. It may play an important role in spermatogenesis. This nuclear enzyme is thought to be activated by autophosphorylation on Ser-219. Expression is predominantly in testis and prostate, with highest concentrations in nongerminal Sertoli cells.Synonyms: Dual specificity testis-specific protein kinase 2, Testicular protein kinase 2

Gene ID: 10420, 9606

UniProt: Q96S53

Pathways: Cell-Cell Junction Organization