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Details for Product No. ABIN392641

U2AF Homology Motif (UHM) Kinase 1 (UHMK1) (N-Term), (AA 1-30) antibody

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Antigen
Synonyms KIST, P-CIP2, 4732477C12Rik, 4930500M09Rik, AA673513, AI449218, AU021979, KIS, Kist, UHMK1, zgc:153241
Epitope
»Alternatives N-Term, AA 1-30
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN392641
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This KIST (KIS) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from the N-terminal region of human KIST (KIS).
Clone RB3367
Isotype Ig
Specificity This KIS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of human KIS.
Predicted Reactivity Rat (Rattus)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name KIST (KIS)
Background Upon serum stimulation, KIS, a member of the Ser/Thr protein kinase family, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. This protein, which contains 1 RRM (RNA recognition motif)domain, may be involved in trafficking and/or processing of RNA. KIS is widely expressed, with highest levels in skeletal muscle, kidney, placenta and peripheral blood leukocytes.
Synonyms: Serine/threonine-protein kinase Kist, Kinase interacting with stathmin, U2AF homology motif kinase 1, UHMK1
Molecular Weight 46546 DA
Gene ID 127933
UniProt Q8TAS1
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Cycle, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Boehm, Yoshimoto, Crook et al.: "A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression." in: The EMBO journal, Vol. 21, Issue 13, pp. 3390-401, 2002 (PubMed).

Bièche, Manceau, Curmi et al.: "Quantitative RT-PCR reveals a ubiquitous but preferentially neural expression of the KIS gene in rat and human." in: Brain research. Molecular brain research, Vol. 114, Issue 1, pp. 55-64, 2003 (PubMed).

Alternatives for antigen "U2AF Homology Motif (UHM) Kinase 1 (UHMK1)", type "Antibodies"
Hosts (29), (8), (2)
Reactivities (35), (23), (16), (13), (12), (2), (1)
Applications (27), (13), (10), (6), (4), (2), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (4), (4), (3), (2), (1), (1)
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