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Lysine (K)-Specific Demethylase 6B (Kdm6b) (N-Term) antibody

Details for Product No. ABIN405298
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Antigen
Synonyms JMJD3, 1700064E03Rik, BC038313, Jmjd3, mKIAA0346, jmjd3, kdm6b, si:ch211-237l4.7
Epitope
N-Term
(23), (9), (7), (7), (6), (5), (5), (4), (2), (2), (2), (2), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Dog (Canine), Human
(45), (30), (7), (1), (1)
Host
Rabbit
(56)
Clonality
Polyclonal
Conjugate
Un-conjugated
(4), (4), (4), (4), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(54), (29), (12), (7), (5), (4), (1)
Pubmed 1 reference available
Quantity 50 µg
Options
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Availability Will be delivered in 2 to 3 Business Days
Catalog No. ABIN405298
289.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Synthetic peptide directed towards the N terminal of human JMJD3
Sequence HRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAW LPGGRCSASI
Predicted Reactivity Human :100 %,   Dog :100 %,   Rat :90 %,   Mouse :90 %,  
Characteristics This is a rabbit polyclonal antibody against JMJD3. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name JMJD3
Background JMJD3 is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It plays a central role in regulation of posterior development, by regulating HOX gene expression. It is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.
Molecular Weight 181 kDa
Gene ID 23135
NCBI Accession NM_001080424, NP_001073893
UniProt O15054
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 1682 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Background publications Hong, Cho, Yu et al.: "Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 47, pp. 18439-44, 2007 (PubMed).

Hosts (56)
Reactivities (45), (30), (7), (1), (1)
Applications (54), (29), (12), (7), (5), (4), (1)
Conjugates (4), (4), (4), (4), (1), (1), (1), (1), (1)
Epitopes (23), (9), (7), (7), (6), (5), (5), (4), (2), (2), (2), (2), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN405298
289.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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