Kdm6b antibody (AA 879-912)
Quick Overview for Kdm6b antibody (AA 879-912) (ABIN6243706)
Target
See all Kdm6b AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 879-912
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This KDM6B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 879-912 amino acids from the Central region of human KDM6B.
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Isotype
- Ig Fraction
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Application Notes
- WB: 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Expiry Date
- 6 months
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- Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))
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Alternative Name
- KDM6B
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Background
- Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.
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Molecular Weight
- 176632
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UniProt
- O15054
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Pathways
- Warburg Effect
Target
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