ER Lipid Raft Associated 2 (ERLIN2) (Middle Region) antibody

Details for Product No. ABIN406694
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Antigen
Synonyms C8orf2, Erlin-2, NET32, SPFH2, SPG18, RGD1309010, Spfh2, BC036333, C87251
Epitope
Middle Region
(12), (7), (3), (1), (1), (1), (1), (1), (1)
Reactivity
Rat (Rattus), Mouse (Murine), Fruit Fly (Drosophila melanogaster), Pig (Porcine), Human
(38), (15), (14), (12), (12), (12), (12)
Host
Rabbit
(33), (5)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(29), (13), (10), (6), (3), (2), (2), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN406694
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Immunogen Synthetic peptide directed towards the middle region of human ERLIN2
Sequence ASNSKIYFGK DIPNMFMDSA GSVSKQFEGL ADKLSFGLED EPLETATKEN
Predicted Reactivity Human : 100 %, Rabbit : 100 %, Pig : 70 %
Characteristics This is a rabbit polyclonal antibody against ERLIN2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name ERLIN2
Background ERLIN2 plays an important role in the early steps of the endoplasmic reticulum-associated degradation (ERAD) pathway. It is involved in ITPR1 degradation by the ERAD pathway.
Molecular Weight 38 kDa
Gene ID 11160
NCBI Accession NP_009106, NM_007175
UniProt O94905
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 339 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-ER Lipid Raft Associated 2 (ERLIN2) (Middle Region) antibody WB Suggested Anti-ERLIN2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: 293T cell lysate
anti-ER Lipid Raft Associated 2 (ERLIN2) (Middle Region) antibody (2) anti-ER Lipid Raft Associated 2 (ERLIN2) (Middle Region) antibody (Image 2)
anti-ER Lipid Raft Associated 2 (ERLIN2) (Middle Region) antibody (3) Host: Rabbit
Target Name: ERLIN2
Sample Tissue: 721_B
Antibody Dilution: 1.0 µg/mL ERLIN2 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells
anti-ER Lipid Raft Associated 2 (ERLIN2) (Middle Region) antibody (4) Host: Rabbit
Target Name: ERLIN2
Sample Tissue: Human Adult Placenta
Antibody Dilution: 1.0 µg/mL
anti-ER Lipid Raft Associated 2 (ERLIN2) (Middle Region) antibody (5) Host: Rabbit
Target Name: ERLIN2
Sample Tissue: Human Fetal Heart
Antibody Dilution: 1.0 µg/mL
anti-ER Lipid Raft Associated 2 (ERLIN2) (Middle Region) antibody (6) Host: Rabbit
Target Name: ERLIN2
Sample Tissue: Human Fetal Brain
Antibody Dilution: 1.0 µg/mL
Background publications Pearce, Wang, Kelley et al.: "SPFH2 mediates the endoplasmic reticulum-associated degradation of inositol 1,4,5-trisphosphate receptors and other substrates in mammalian cells." in: The Journal of biological chemistry, Vol. 282, Issue 28, pp. 20104-15, 2007 (PubMed).

Validation Images
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