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ERLIN2 antibody (AA 212-339)

ERLIN2 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7151997
  • Target See all ERLIN2 Antibodies
    ERLIN2 (ER Lipid Raft Associated 2 (ERLIN2))
    Binding Specificity
    • 14
    • 11
    • 5
    • 2
    • 2
    • 1
    • 1
    AA 212-339
    Reactivity
    • 33
    • 4
    • 4
    • 2
    • 2
    • 1
    Human
    Host
    • 30
    • 2
    • 1
    Rabbit
    Clonality
    • 30
    • 3
    Polyclonal
    Conjugate
    • 19
    • 4
    • 3
    • 3
    • 2
    • 2
    This ERLIN2 antibody is un-conjugated
    Application
    • 27
    • 19
    • 10
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human
    Purification
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Erlin-2 protein (212-339AA)
    Isotype
    IgG
    Top Product
    Discover our top product ERLIN2 Primary Antibody
  • Application Notes
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    ERLIN2 (ER Lipid Raft Associated 2 (ERLIN2))
    Alternative Name
    ERLIN2 (ERLIN2 Products)
    Synonyms
    C8orf2 antibody, Erlin-2 antibody, NET32 antibody, SPFH2 antibody, SPG18 antibody, BC036333 antibody, C87251 antibody, Spfh2 antibody, Erlin-2-B antibody, erlin1 antibody, spfh1 antibody, spfh2 antibody, spfh2-B antibody, RGD1309010 antibody, SPFH domain-containing protein 2-A antibody, erlin2 antibody, erlin2-a antibody, erlin2-b antibody, spfh2-A antibody, ER lipid raft associated 2 antibody, erlin-2 antibody, Erlin-2 antibody, ER lipid raft associated 2 S homeolog antibody, ER lipid raft associated 2 L homeolog antibody, ERLIN2 antibody, erlin2 antibody, Tsp_03442 antibody, erln2 antibody, Erlin2 antibody, erlin2.S antibody, erlin2.L antibody
    Background

    Background: Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1 (PubMed:19240031, PubMed:17502376). Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex (PubMed:21343306). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex (PubMed:24217618).

    Aliases: C8orf2 antibody, Chromosome 8 open reading frame 2 antibody, Endoplasmic reticulum lipid raft associated protein 2 antibody, Endoplasmic reticulum lipid raft-associated protein 2 antibody, ER lipid raft associated 2 antibody, ERLIN 2 antibody, Erlin-2 antibody, ERLIN2 antibody, ERLN2_HUMAN antibody, HGNC:1356 antibody, MGC87072 antibody, NET32 antibody, SPFH 2 antibody, SPFH domain containing protein 2 antibody, SPFH domain family member 2 antibody, SPFH domain-containing protein 2 antibody, SPFH2 antibody, SPG18 antibody, Stomatin prohibitin flotillin HflC/K domain containing protein 2 antibody, Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2 antibody

    UniProt
    O94905
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