POU3F3 antibody (N-Term)
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- Target See all POU3F3 Antibodies
- POU3F3 (POU Class 3 Homeobox 3 (POU3F3))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This POU3F3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- GGGGGGGGGA GGGGGGMQPG SAAVTSGAYR GDPSSVKMVQ SDFMQGAMAA
- Predicted Reactivity
- Human: 100%, Mouse: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against POU3F3. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human POU3F3
- Top Product
- Discover our top product POU3F3 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 500 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- POU3F3 (POU Class 3 Homeobox 3 (POU3F3))
- Alternative Name
- POU3F3 (POU3F3 Products)
- Synonyms
- BRN1 antibody, OTF8 antibody, Brn1 antibody, RHS1 antibody, Brn-1 antibody, Otf8 antibody, Skin1 antibody, brn1 antibody, nrl-20 antibody, nrl20-A antibody, pou1 antibody, pou23 antibody, wu:fb92g06 antibody, zfpou1 antibody, zp23 antibody, zp23pou antibody, BRN-1.1 antibody, ZP12POU antibody, brn1.1 antibody, pou12 antibody, wu:fc33a11 antibody, zp12 antibody, POU class 3 homeobox 3 antibody, POU domain, class 3, transcription factor 3 antibody, POU class 3 homeobox 3 S homeolog antibody, POU class 3 homeobox 3b antibody, POU class 3 homeobox 3a antibody, POU3F3 antibody, Pou3f3 antibody, pou3f3.S antibody, pou3f3b antibody, pou3f3a antibody
- Background
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POU3F3 is the transcription factor that acts synergistically with SOX11 and SOX4. POU3F3 plays a role in neuronal development. POU3F3 is implicated in an enhancer activity at the embryonic met-mesencephalic junction, the enhancer element contains the octamer motif (5'-ATTTGCAT-3').POU3F3 is a member of the class III POU family of transcription factors (see POU3F1, MIM 602479) that are expressed in the central nervous system. The POU domain in these proteins is required for high affinity binding to octamer DNA sequences Sumiyama et al. (1996) [PubMed 8703082].[supplied by OMIM].
Alias Symbols: BRN1, OTF8
Protein Interaction Partner: Dlg4, SOX8, PPP1R15A, SOX10, SOX11, POU3F4,
Protein Size: 500 - Molecular Weight
- 50 kDa
- Gene ID
- 5455
- NCBI Accession
- NM_006236, NP_006227
- UniProt
- P20264
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