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Details for Product No. ABIN487123

Cholesterol Esterase (Middle Region) antibody

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Antigen
Synonyms BAL, BSDL, BSSL, CELL, CEase, FAP, FAPP, LIPA, MODY8, 1810036E18Rik, Bal, Bssl, SC8F4.24
Epitope
»Alternatives Middle Region
Reactivity
»Alternatives Rat (Rattus), Mouse (Murine), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN487123
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-CEL antibody: synthetic peptide directed towards the middle region of human CEL
Sequence VTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPPTDDS KEAQMPAVIR
Predicted Reactivity Human : 100%, Rat : 100%, Mouse : 76%
Characteristics This is a rabbit polyclonal antibody against CEL. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Affinity Purified
Alternative Name CEL
Background CEL catalyzes fat and vitamin absorption. CEL acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides.The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein.
Molecular Weight 80kDa
Gene ID 1056
NCBI Accession NP_001798, NM_001807
UniProt P19835
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-CEL antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Product cited in: Panicot-Dubois, Thomas, Furie et al.: "Bile salt-dependent lipase interacts with platelet CXCR4 and modulates thrombus formation in mice and humans." in: The Journal of clinical investigation, Vol. 117, Issue 12, pp. 3708-19, 2007 (PubMed).

Alternatives for antigen "Cholesterol Esterase", type "Antibodies"
Hosts (30), (6)
Reactivities (23), (12), (12), (12), (12), (12), (12), (9), (3), (3)
Applications (23), (21), (10), (8), (6), (3), (3), (1), (1)
Conjugates (5), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (2), (2), (2), (2), (1), (1)
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