Cholesterol Esterase antibody (AA 454-482)

Catalog No. ABIN656486

The Rabbit Polyclonal anti-Cholesterol Esterase antibody is suitable to detect Cholesterol Esterase in samples from Human. It has been validated for WB.

Quick Overview for Cholesterol Esterase antibody (AA 454-482) (ABIN656486)

Target: Cholesterol Esterase (CEL)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cholesterol Esterase antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB31034

Product Details anti-Cholesterol Esterase Antibody

Binding Specificity: AA 454-482

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CEL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 454-482 amino acids from the Central region of human CEL.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for Cholesterol Esterase

Target: Cholesterol Esterase (CEL)

Alternative Name: CEL

Background: The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein.

Molecular Weight: 79322

UniProt: P19835

Pathways: Lipid Metabolism