ARHGAP18 antibody (C-Term)

Catalog No. ABIN499333

Product Details anti-ARHGAP18 Antibody

Target: ARHGAP18 (rho GTPase Activating Protein 18 (ARHGAP18))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGAP18 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogen: ARHGAP18 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human ARHGAP18.

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: ARHGAP18 antibody can be used for detection of ARHGAP18 at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for ARHGAP18

Target: ARHGAP18 (rho GTPase Activating Protein 18 (ARHGAP18))

Alternative Name: ARHGAP18 (ARHGAP18 Products)

Background: ARHGAP18 is one member of the human RhoGAP family with approximately 80 RhoGAP proteins known to be encoded in the human genome. Rho proteins belong to the Ras superfamily that is composed of over 50 members divided into six families, including Ras, Sar, Rho, Ran, Rab and Arf. Rho GTPases are important regulators of the actin cytoskeleton and consequently influence the shape and migration of cells. ARHGAP18 is linked to Ras, and thus, to EGFR-mediated proliferation, migration and differentiation. ARHGAP18 is precisely contained within chromosome 6q22-24, which has been shown to be linked to schizophrenia, suggesting that ARHGEP18 may play a role in this condition.Synonyms: MacGAP, Rho GTPase-activating protein 18, Rho-type GTPase-activating protein 18

Gene ID: 93663

NCBI Accession: NP_277050

UniProt: Q8N392