rho GTPase Activating Protein 18 (ARHGAP18) (C-Term) antibody

Details for Product No. ABIN499333
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Synonyms AI314906, AI843501, 4833419J07Rik, MacGAP, SENEX, bA307O14.2, MGC146282, DKFZp469I1011
(14), (2), (1), (1), (1), (1)
Human, Mouse (Murine), Rat (Rattus)
(24), (10), (10)
Immunocytochemistry (ICC), Immunofluorescence (IF), ELISA, Western Blotting (WB)
(24), (20), (13), (9), (4), (3), (1)
Pubmed 1 reference available
Catalog no. ABIN499333
Quantity 0.1 mg
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Immunogen ARHGAP18 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human ARHGAP18. (AP30079CP-N)
Isotype IgG
Purification Affinity chromatography purified via peptide column
Alternative Name ARHGAP18
Background ARHGAP18 is one member of the human RhoGAP family with approximately 80 RhoGAP proteins known to be encoded in the human genome. Rho proteins belong to the Ras superfamily that is composed of over 50 members divided into six families, including Ras, Sar, Rho, Ran, Rab and Arf. Rho GTPases are important regulators of the actin cytoskeleton and consequently influence the shape and migration of cells. ARHGAP18 is linked to Ras, and thus, to EGFR-mediated proliferation, migration and differentiation. ARHGAP18 is precisely contained within chromosome 6q22-24, which has been shown to be linked to schizophrenia, suggesting that ARHGEP18 may play a role in this condition.
Alternate names: MacGAP, Rho GTPase-activating protein 18, Rho-type GTPase-activating protein 18
Gene ID 93663
NCBI Accession NP_277050
UniProt Q8N392
Application Notes ELISA. Western Blot: ARHGAP18 antibody can be used for detection of ARHGAP18 at 1 - 2 μg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS containing 0.02% sodium azide.
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at -20°C.
Expiry Date 12 months
Background publications Takai, Sasaki, Matozaki: "Small GTP-binding proteins." in: Physiological reviews, Vol. 81, Issue 1, pp. 153-208, 2001 (PubMed).

Hosts (24)
Reactivities (24), (10), (10)
Applications (24), (20), (13), (9), (4), (3), (1)
Epitopes (14), (2), (1), (1), (1), (1)
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