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Details for Product No. ABIN501436

Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2) (Middle Region) antibody

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Antigen
Synonyms CACNLB2, CAVB2, MYSB, AW060387, CAB2, Cavbeta2, Cchb2, Cacnlb2, Cacnb2, CACNB2
Epitope
»Alternatives Middle Region
Reactivity
»Alternatives Rabbit, Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Xenopus laevis, Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN501436
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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anti-Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2) (Middle Region) antibody

Product details

Target Details Application Details Handling Images References Alternatives back to top
Immunogen The immunogen for anti-CACNB2 antibody: synthetic peptide directed towards the middle region of human CACNB2
Sequence DACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPL SPTLASNSQG
Predicted Reactivity Bovine : 100%, Horse : 100%, Human : 100%, Mouse : 100%, Pig : 100%, Dog : 93%, Guinea pig : 92%, Rat : 92%
Characteristics This is a rabbit polyclonal antibody against CACNB2. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Affinity Purified

Target Details

Application Details Handling Images References Alternatives back to top
Alternative Name CACNB2
Background CACNB2 belongs to the calcium channel beta subunit family.The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.Defects in CACNB2 are the cause of Brugada syndrome type 4 (BRS4).
Molecular Weight 68kDa
Gene ID 783
NCBI Accession NP_963866, NM_201572
UniProt A6PVM7
Research Area Neurology

Application Details

Target Details Handling Images References Alternatives back to top
Restrictions For Research Use only

Handling

Target Details Application Details Images References Alternatives back to top
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-CACNB2 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C

References

Target Details Application Details Handling Images Alternatives back to top
Background publications Uhl, Liu, Drgon et al.: "Molecular genetics of successful smoking cessation: convergent genome-wide association study results." in: Archives of general psychiatry, Vol. 65, Issue 6, pp. 683-93, 2008 (PubMed).

Alternatives

Target Details Application Details Handling Images References back to top
Alternatives for antigen "Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2)", type "Antibodies"
Hosts (61), (16), (3)
Reactivities (65), (29), (27), (17), (14), (8), (7), (1)
Applications (66), (21), (10), (6), (5), (3), (2), (2), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (12), (9), (9), (8), (4), (3), (3), (2), (2), (1)
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