CACNB2 antibody (Middle Region)

Catalog No. ABIN501436

Product Details anti-CACNB2 Antibody

Target: CACNB2 (Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Cow, Rabbit, Guinea Pig, Horse, Dog, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACNB2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DACEHLADYL EAYWKATHPP SSSLPNPLLS RTLATSSLPL SPTLASNSQG

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 82%

Characteristics: This is a rabbit polyclonal antibody against CACNB2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CACNB2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 608 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CACNB2

Target: CACNB2 (Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2))

Alternative Name: CACNB2 (CACNB2 Products)

Background: CACNB2 belongs to the calcium channel beta subunit family.The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.Defects in CACNB2 are the cause of Brugada syndrome type 4 (BRS4).
Alias Symbols: CACNLB2, FLJ23743, MYSB, CAVB2
Protein Interaction Partner: REM1, PRKACA,
Protein Size: 608

Molecular Weight: 68 kDa

Gene ID: 783

NCBI Accession: NM_201572, NP_963866

UniProt: A6PVM7

Pathways: Skeletal Muscle Fiber Development