CACNB2 antibody (AA 189-205) (PerCP)

Catalog No. ABIN2485042

The Mouse Monoclonal anti-CACNB2 antibody is suitable to detect CACNB2 in samples from Rat. It has been validated for WB, IHC, IP, IF, ICC and AA.

Quick Overview for CACNB2 antibody (AA 189-205) (PerCP) (ABIN2485042)

Target: CACNB2 (Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CACNB2 antibody is conjugated to PerCP

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Antibody Array (AA)

Clone: N8b-1 (Formerly S8B-1)

Product Details anti-CACNB2 Antibody (PerCP)

Binding Specificity: AA 189-205

Specificity: Detects ~78 kDa. No cross reactivity against Cavβ1, Cavβ3, Cavβ4.

Cross-Reactivity: Human, Mouse, Rat

Purification: Protein G Purified

Immunogen: Synthetic peptide amino acids 189-205 of rat CavBeta2

Isotype: IgG1

Application Details

Application Notes:

• WB (1:1000)
• IHC (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Comment:

1 μg/ml of ABIN2485042 was sufficient for detection of Cavβ2 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Conjugated antibodies should be stored at 4°C

Target Details for CACNB2

Target: CACNB2 (Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2))

Alternative Name: CavBeta2

Background: Cav Beat subunits are involved in the transport of the pore forming alpha1 subunit to the plasma membrane (1). They also shield an ER Retention signal on the alpha1 subunit, thereby guiding the pore-forming subunit to the target membrane (2, 3). They also determine the biophysical properties of the calcium channel (3).

Gene ID: 116600

NCBI Accession: NP_446303

UniProt: Q8VGC3

Pathways: Skeletal Muscle Fiber Development