Exosome Component 10 (EXOSC10) (C-Term) antibody

Details for Product No. ABIN501939
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Antigen
Synonyms
Pmscl2, zgc:55695, pm-scl, pm/scl-100, pmscl, pmscl2, rrp6, rrp6p, EXOSC10, 201.t00018, 21.m02990, DDBDRAFT_0203581, DDBDRAFT_0233752, DDB_0203581, DDB_0233752, PM-Scl, PM/Scl-100, PMSCL, PMSCL2, RRP6 ... show more
Pmscl2, zgc:55695, pm-scl, pm/scl-100, pmscl, pmscl2, rrp6, rrp6p, EXOSC10, 201.t00018, 21.m02990, DDBDRAFT_0203581, DDBDRAFT_0233752, DDB_0203581, DDB_0233752, PM-Scl, PM/Scl-100, PMSCL, PMSCL2, RRP6, Rrp6p, p2, p3, p4 show less
Epitope
C-Term
(3), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Cow (Bovine), Human
(28), (16), (16), (13), (12), (12), (1)
Host
Rabbit
(26), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(17), (10), (6), (5), (4), (3), (1), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN501939
289.00 $
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Immunogen Synthetic peptide directed towards the middle region of human EXOSC10
Sequence ACKAAAEQAI SVRQQVVLEN AAKKRERATS DPRTTEQKQE KKRLKISKKP
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Rabbit : 100 %, Horse : 90 %, Mouse : 80 %
Characteristics This is a rabbit polyclonal antibody against EXOSC10. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name EXOSC10
Background EXOSC10 contains 1 HRDC domain and 1 3'-5' exonuclease domain. Antibodies against PM/SCL are found in patients with polymyositis and/or scleroderma.
Molecular Weight 101 kDa
Gene ID 5394
NCBI Accession NP_001001998, NM_001001998
UniProt Q01780
Research Area Chromatin and Nuclear Signaling, DNA/RNA
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 885 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Product cited in: van Dijk, Schilders, Pruijn: "Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways." in: RNA (New York, N.Y.), Vol. 13, Issue 7, pp. 1027-35, 2007 (PubMed).

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