Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

EXOSC10 Antibodies

(Exosome Component 10 (EXOSC10))
Putative catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. EXOSC10 has 3'-5' exonuclease activity (By similarity). EXOSC10 is required for nucleolar localization of C1D and probably mediates the association of SKIV2L2, C1D and MPP6 wth the RNA exosome involved in the maturation of 5.8S rRNA (By similarity).
EXOSC10 antibody  (C-Term) EXOSC10 antibody  (C-Term) EXOSC10 antibody (C-Term) (ABIN2778684)

EXOSC10 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit WB Host: Rabbit Polyclonal unconjugated

EXOSC10 antibody  (C-Term) EXOSC10 antibody  (C-Term) EXOSC10 antibody (C-Term) (ABIN2778683)

EXOSC10 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit IHC, WB Host: Rabbit Polyclonal unconjugated

EXOSC10 antibody  (C-Term) EXOSC10 antibody  (C-Term) EXOSC10 antibody (C-Term) (ABIN629904)

EXOSC10 Reactivity: Human IHC, WB Host: Rabbit Polyclonal unconjugated

EXOSC10 Antibodies by Reactivity

Find EXOSC10 Antibodies for a variety of species such as anti-Human EXOSC10, anti-Mouse EXOSC10, anti-Cow EXOSC10. The species listed below are among those available. Click on a link to go to the corresponding products.

EXOSC10 Antibodies by Application

Find EXOSC10 Antibodies validated for a specific application such as WB, IF (cc), IF (p), ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

EXOSC10 Antibodies by Host

Find EXOSC10 Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

EXOSC10 Antibodies by Binding Specificity

Find EXOSC10 Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

EXOSC10 Antibodies by Clonality

Find available monoclonal or polyclonal EXOSC10 Antibodies. Click on a link to go to the corresponding products.

EXOSC10 Antibodies by Clone

Find EXOSC10 Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

EXOSC10 Antibodies by Conjugate

Find EXOSC10 Antibodies with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular EXOSC10 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application ELISA, ICC, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (2)
Cat. No. ABIN1714746
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Human, Mouse, Rabbit
Application IHC, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN203030
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (2)
Cat. No. ABIN518993
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN633246
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Human, Mouse, Rabbit
Application IHC, IHC (p), WB
Validations
  • (1)
Cat. No. ABIN6756542
Quantity 100 μL
Datasheet Datasheet
Reactivity Saccharomyces cerevisiae
Application ELISA, WB
Validations
Cat. No. ABIN7179188
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IF, IHC, IP, WB
Validations
Cat. No. ABIN7114009
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN7267062
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
Cat. No. ABIN7094210
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application IHC (fro), IHC (p), WB
Validations
Cat. No. ABIN1701244
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application IF (cc), IF (p)
Validations
Cat. No. ABIN1695800
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application IF (cc), IF (p)
Validations
Cat. No. ABIN1699430
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application IF (cc), IF (p)
Validations
Cat. No. ABIN1697619
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application IF (cc), IF (p)
Validations
Cat. No. ABIN1693976
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application IF (cc), IF (p)
Validations
Cat. No. ABIN1703056
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our EXOSC10 Antibodies

Ogami, Richard, Chen, Hoque, Li, Moresco, Yates, Tian, Manley: "An Mtr4/ZFC3H1 complex facilitates turnover of unstable nuclear RNAs to prevent their cytoplasmic transport and global translational repression." in: Genes & development, (2017) (PubMed).

Hsin, Li, Hoque, Tian, Manley: "RNAP II CTD tyrosine 1 performs diverse functions in vertebrate cells." in: eLife, Vol. 3, pp. e02112, (2014) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Richard, Feng, Manley: "A SUMO-dependent interaction between Senataxin and the exosome, disrupted in the neurodegenerative disease AOA2, targets the exosome to sites of transcription-induced DNA damage." in: Genes & development, Vol. 27, Issue 20, pp. 2227-32, (2013) (PubMed).

van Dijk, Schilders, Pruijn: "Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways." in: RNA (New York, N.Y.), Vol. 13, Issue 7, pp. 1027-35, (2007) (PubMed).

Aliases for EXOSC10 Antibodies

exosome component 10 (exosc10) Antibodies
exosome component 10 (EXOSC10) Antibodies
exosome component 10 (EHI_021400) Antibodies
exosome component 10 (BBOV_IV002650) Antibodies
exosome component 10 (CpipJ_CPIJ003896) Antibodies
exosome component 10 (CMU_031760) Antibodies
3'-5' exonuclease (exosc10) Antibodies
exosome component 10 (Tsp_05247) Antibodies
exosome component 10 L homeolog (exosc10.L) Antibodies
exosome component 10 (Exosc10) Antibodies
21.m02990 Antibodies
201.t00018 Antibodies
DDBDRAFT_0203581 Antibodies
DDBDRAFT_0233752 Antibodies
DDB_0203581 Antibodies
DDB_0233752 Antibodies
EXOSC10 Antibodies
p2 Antibodies
p3 Antibodies
p4 Antibodies
pm-scl Antibodies
PM-Scl Antibodies
pm/scl-100 Antibodies
PM/Scl-100 Antibodies
pmscl Antibodies
PMSCL Antibodies
Pmscl2 Antibodies
pmscl2 Antibodies
PMSCL2 Antibodies
rrp6 Antibodies
RRP6 Antibodies
rrp6p Antibodies
Rrp6p Antibodies
zgc:55695 Antibodies
You are here:
Support