NIMA (Never In Mitosis Gene A)-Related Kinase 11 (NEK11) (Middle Region) antibody

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Antigen
Synonyms nek11, MGC147549, 4932416N14Rik
Epitope
Middle Region
(8), (5), (4), (2), (2), (1), (1)
Reactivity
Human, Rat (Rattus)
(34), (4), (3)
Host
Rabbit
(19), (15)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(33), (14), (12), (4), (4), (2), (2), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the middle region of human NEK11
Sequence KEIRNEGSQP AYRTNQQDSD IEALARCLEN VLGCTSLDTK TITTMAEDMS
Predicted Reactivity Horse : 100 %, Human : 100 %, Rat : 70 %, Bovine : 70 %
Characteristics This is a rabbit polyclonal antibody against NEK11. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name NEK11 (NEK11 Antibody Abstract)
Background NEK11 is a member of the never in mitosis gene A family of kinases. NEK11 localizes to the nucleoli, and may function with NEK2A in the S-phase checkpoint. It appears to play roles in DNA replication and response to genotoxic stress. NEK11 belongs to the NIMA family of kinases, which are involved in DNA replication and genotoxic stress responses (Noguchi et al., 2002 [PubMed 12154088]).
Molecular Weight 74 kDa
Gene ID 79858
NCBI Accession NP_079076, NM_024800
UniProt Q8NG66
Research Area Signaling
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 645 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-NIMA (Never In Mitosis Gene A)-Related Kinase 11 (NEK11) (Middle Region) antibody (ABIN502997) WB Suggested Anti-NEK11 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Western Blotting (WB) image for anti-NIMA (Never In Mitosis Gene A)-Related Kinase 11 (NEK11) (Middle Region) antibody (ABIN502997) Host: Rabbit
Target Name: NEK11
Sample Tissue: Human Fetal Heart
...
Western Blotting (WB) image for anti-NIMA (Never In Mitosis Gene A)-Related Kinase 11 (NEK11) (Middle Region) antibody (ABIN502997) Host: Rabbit
Target Name: NEK11
Sample Tissue: Human Fetal Lung
...
Western Blotting (WB) image for anti-NIMA (Never In Mitosis Gene A)-Related Kinase 11 (NEK11) (Middle Region) antibody (ABIN502997) Host: Rabbit
Target Name: NEK11
Sample Tissue: Human Fetal Muscle
Western Blotting (WB) image for anti-NIMA (Never In Mitosis Gene A)-Related Kinase 11 (NEK11) (Middle Region) antibody (ABIN502997) Host: Rabbit
Target Name: NEK11
Sample Tissue: Human Adult Placenta
Background publications Uhl, Liu, Drgon et al.: "Molecular genetics of successful smoking cessation: convergent genome-wide association study results." in: Archives of general psychiatry, Vol. 65, Issue 6, pp. 683-93, 2008 (PubMed).

Catalog No. ABIN502997
$289.00
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