TP53 Apoptosis Effector (PERP) (Middle Region) antibody

Details for Product No. ABIN503057
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Antigen
Synonyms PERP, PERPL, kcp1, krtcap1, pigpc1, thw, fk24g11, wu:fk24g11, LOC100221212, 1110017A08Rik, KCP1, KRTCAP1, PIGPC1, THW, RP3-496H19.1, dJ496H19.1
Epitope
Middle Region
(23), (7), (5), (3), (2), (1), (1), (1), (1)
Reactivity
Human
(39), (3), (2), (1)
Host
Rabbit
(37), (4)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(39), (18), (10), (10), (5), (4), (1), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN503057
289.00 $
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Immunogen Synthetic peptide directed towards the middle region of human PERP
Sequence FLRVIGGLLA LAAVFQIISL VIYPVKYTQT FTLHANPAVT YIYNWAYGFG
Predicted Reactivity Human : 100 %, Horse : 90 %, Bovine : 80 %, Dog : 80 %, Mouse : 80 %, Pig : 80 %, Rat : 80 %
Characteristics This is a rabbit polyclonal antibody against PERP. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name PERP
Background PERP is a component of intercellular desmosome junctions. PERP plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. PERP also plays a role as an effector in the TP53-dependent apoptotic pathway.
Molecular Weight 21 kDa
Gene ID 64065
NCBI Accession NP_071404, NM_022121
UniProt Q96FX8
Research Area Signaling, Extracellular Matrix, Apoptosis/Necrosis
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 193 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-TP53 Apoptosis Effector (PERP) (Middle Region) antibody WB Suggested Anti-PERP Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: PANC1 cell lysate
anti-TP53 Apoptosis Effector (PERP) (Middle Region) antibody (2) WB Suggested Anti-PERP
Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500
Positive Control: PANC1 cell lysate
PERP is supported by BioGPS gene expression data to be expressed in PANC1
Background publications Ihrie, Attardi: "Perp-etrating p53-dependent apoptosis." in: Cell cycle (Georgetown, Tex.), Vol. 3, Issue 3, pp. 267-9, 2004 (PubMed).

Validation Images
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