PERP antibody (Middle Region)

Catalog No. ABIN2783850

The Rabbit Polyclonal anti-PERP antibody is suitable to detect PERP in samples from Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig and Rabbit. It has been validated for WB and IHC.

Quick Overview for PERP antibody (Middle Region) (ABIN2783850)

Target: PERP (TP53 Apoptosis Effector (PERP))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PERP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PERP Antibody

Binding Specificity: Middle Region

Purpose: PERP Antibody - middle region

Sequence: FLRVIGGLLA LAAVFQIISL VIYPVKYTQT FTLHANPAVT YIYNWAYGFG

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against PERP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PERP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49688-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PERP

Target: PERP (TP53 Apoptosis Effector (PERP))

Alternative Name: PERP

Background:

Background Information: PERP is a component of intercellular desmosome junctions. PERP plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. PERP also plays a role as an effector in the TP53-dependent apoptotic pathway.

Gene Name: PERP, TP53 apoptosis effector

Alternative Symbols: THW, KCP1, EKVP7, OLMS2, PIGPC1, KRTCAP1, dJ496H19.1

Protein Name: p53 apoptosis effector related to PMP-22

Molecular Weight: 21kDa

Gene ID: 64065

NCBI Accession: NP_071404

UniProt: Q96FX8

Pathways: Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity