Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1) (C-Term) antibody

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Antigen
Synonyms DDBDRAFT_0219393, DDBDRAFT_0231375, DDB_0219393, DDB_0231375, 26kDa, D5Ertd406e, EIF2B, EIF2BA, eIF-2a
Epitope
C-Term
(16), (13), (9), (3), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)
(33), (6), (6)
Host
Rabbit
(30), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB)
(30), (18), (16), (15), (6), (5), (2), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the C terminal of human EIF2B1
Blocking Peptide Blocking peptide for this product available: Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1) peptide (ABIN976206)
Sequence ADTLKVAQTG QDLKEEHPWV DYTAPSLITL LFTDLGVLTP SAVSDELIKL
Predicted Reactivity Mouse : 85 %, Dog : 75 %, Pig : 75 %, Rabbit : 75 %
Characteristics This is a rabbit polyclonal antibody against EIF2B1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name EIF2B1 (EIF2B1 Antibody Abstract)
Background EIF2B1 belongs to the EIF-2B alpha/beta/delta subunits family. It catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. Defects in EIF2B1 are a cause of leukoencephalopathy with vanishing white matter (VWM).
Molecular Weight 34 kDa
Gene ID 1967
NCBI Accession NM_001414, NP_001405
UniProt Q14232
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 305 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1) (C-Term) antibody (ABIN503287) WB Suggested Anti-EIF2B1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Western Blotting (WB) image for anti-Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1) (C-Term) antibody (ABIN503287) WB Suggested Anti-EIF2B1
Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500 ...
Background publications Maletkovic, Schiffmann, Gorospe et al.: "Genetic and clinical heterogeneity in eIF2B-related disorder." in: Journal of child neurology, Vol. 23, Issue 2, pp. 205-15, 2008 (PubMed).

Catalog No. ABIN503287
$289.00
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