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Myotubularin Related Protein 12 (MTMR12) (Middle Region) antibody

Details for Product No. ABIN503906, Supplier: Login to see New
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Synonyms PIP3AP, MTMR12, 3-PAP, 3Pap, 4932703C11, C730015A02Rik, Pip3ap, mKIAA1682, im:7160376, pip3ap
Middle Region
(3), (1), (1), (1), (1), (1), (1)
Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)
(15), (6), (4), (1)
(12), (2), (1)
Western Blotting (WB)
(13), (5), (2), (1), (1)
Pubmed 1 reference available
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Quantity 50 μg
Shipping to United States ( )
Availability Will be delivered in 2 to 3 Business Days
Immunogen Synthetic peptide directed towards the middle region of human MTMR12
Blocking Peptide Blocking peptide for this product available: ABIN980352
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Guinea pig : 90 %, Pig : 90 %, Rabbit : 90 %, Horse : 80 %
Characteristics This is a rabbit polyclonal antibody against MTMR12. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name MTMR12 (MTMR12 Antibody Abstract)
Background MTMR12 inactives phosphatase that plays a role as an adapter for the phosphatase myotubularin to regulate myotubularin intracellular location.Phosphatidylinositide 3-kinase-derived membrane-anchored phosphatidylinositides, such as phosphatidylinositol 3-phosphate (PtdIns(3)P), regulate diverse cellular processes. The protein encoded by this gene functions as an adaptor subunit in a complex with an active PtdIns(3)P 3-phosphatase. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.
Molecular Weight 86 kDa
Gene ID 54545
NCBI Accession NM_001040446, NP_001035536
UniProt Q9C0I1
Application Notes Optimal working dilutions should be determined experimentally by the investigator.

Antigen size: 747 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Myotubularin Related Protein 12 (MTMR12) (Middle Region) antibody (ABIN503906) WB Suggested Anti-MTMR12 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Background publications Nandurkar, Layton, Laporte et al.: "Identification of myotubularin as the lipid phosphatase catalytic subunit associated with the 3-phosphatase adapter protein, 3-PAP." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 15, pp. 8660-5, 2003 (PubMed).

Catalog No. ABIN503906
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