Patatin-Like phospholipase Domain Containing 8 (PNPLA8) (Middle Region) antibody

Details for Product No. ABIN504075
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Antigen
Synonyms IPLA2(GAMMA), IPLA2-2, IPLA2G, iPLA2gamma, 1200006O19Rik, AI467579, Ipla2(gamma), RGD1311444, iPLA2
Epitope
Middle Region
(7), (6), (2), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Human
(19), (7)
Host
Rabbit
(20)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(20), (16), (7), (3)
Pubmed 2 references available
Quantity 50 µg
Options
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Catalog No. ABIN504075
289.00 $
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Immunogen Synthetic peptide directed towards the middle region of human PNPLA8
Sequence IDNRTRALVQ ALRRTTDPKL CITRVEELTF HLLEFPEGKG VAVKERIIPY
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Chicken : 90 %, Zebrafish : 90 %
Characteristics This is a rabbit polyclonal antibody against PNPLA8. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name PNPLA8
Background Phospholipase A2 catalyzes cleavage of fatty acids from phospholipids, thereby regulating membrane physical properties and the release of lipid second messengers and growth factors. Phospholipase A2 activity also modulates cellular growth programs, inflam
Molecular Weight 88 kDa
Gene ID 50640
NCBI Accession NM_015599, NP_056538
UniProt Q9NP80
Research Area Cardiovascular, Fatty Acids, Metabolism
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 782 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Patatin-Like phospholipase Domain Containing 8 (PNPLA8) (Middle Region) antibody WB Suggested Anti-PNPLA8 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: 293T cell lysate
Product cited in: Ali, Kokotos, Magrioti et al.: "Characterization of FKGK18 as inhibitor of group VIA Ca2+-independent phospholipase A2 (iPLA2β): candidate drug for preventing beta-cell apoptosis and diabetes." in: PLoS ONE, Vol. 8, Issue 8, pp. e71748, 2013 (PubMed).

Background publications Mungall, Palmer, Sims et al.: "The DNA sequence and analysis of human chromosome 6." in: Nature, Vol. 425, Issue 6960, pp. 805-11, 2003 (PubMed).

Validation Images
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