PNPLA8 antibody (Middle Region)

Catalog No. ABIN2786886

Product Details anti-PNPLA8 Antibody

Target: PNPLA8 (Patatin-Like phospholipase Domain Containing 8 (PNPLA8))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Rabbit, Horse, Cow, Dog, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PNPLA8 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IDNRTRALVQ ALRRTTDPKL CITRVEELTF HLLEFPEGKG VAVKERIIPY

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against PNPLA8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PNPLA8

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 782 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PNPLA8 antibody (ABIN2786886)

Ali, Kokotos, Magrioti, Bone, Mobley, Hancock, Ramanadham: "Characterization of FKGK18 as inhibitor of group VIA Ca2+-independent phospholipase A2 (iPLA2β): candidate drug for preventing beta-cell apoptosis and diabetes." in: PLoS ONE, Vol. 8, Issue 8, pp. e71748, (2013) (PubMed).

Target Details for PNPLA8

Target: PNPLA8 (Patatin-Like phospholipase Domain Containing 8 (PNPLA8))

Alternative Name: PNPLA8 (PNPLA8 Products)

Synonyms: IPLA2(GAMMA) antibody, IPLA2-2 antibody, IPLA2G antibody, iPLA2gamma antibody, 1200006O19Rik antibody, AI467579 antibody, Ipla2(gamma) antibody, RGD1311444 antibody, iPLA2 antibody, patatin like phospholipase domain containing 8 antibody, patatin-like phospholipase domain containing 8 antibody, PNPLA8 antibody, Pnpla8 antibody

Background: Phospholipase A2 catalyzes cleavage of fatty acids from phospholipids, thereby regulating membrane physical properties and the release of lipid second messengers and growth factors. Phospholipase A2 activity also modulates cellular growth programs, inflam
Alias Symbols: IPLA2(GAMMA), IPLA2-2, IPLA2G
Protein Interaction Partner: UBC,
Protein Size: 782

Molecular Weight: 88 kDa

Gene ID: 50640

NCBI Accession: NM_015599, NP_056538

UniProt: Q9NP80