AIFM2 antibody (Middle Region)

Catalog No. ABIN504615

Product Details anti-AIFM2 Antibody

Target: AIFM2 (Apoptosis-Inducing Factor, Mitochondrion-Associated, 2 (AIFM2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AIFM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: GALTFLLSMG RNDGVGQISG FYVGRLMVRL TKSRDLFVST SWKTMRQSPP

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 93%, Human: 100%, Mouse: 80%, Rabbit: 93%, Rat: 80%

Characteristics: This is a rabbit polyclonal antibody against AIFM2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human AIFM2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 373 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AIFM2

Target: AIFM2 (Apoptosis-Inducing Factor, Mitochondrion-Associated, 2 (AIFM2))

Alternative Name: AIFM2 (AIFM2 Products)

Background: AIFM2 has significant homology to NADH oxidoreductases and the apoptosis-inducing factor PDCD8/AIF. Overexpression of this gene has been shown to induce apoptosis. The expression of this gene is found to be induced by tumor suppressor protein p53 in colon caner cells. The protein encoded by this gene has significant homology to NADH oxidoreductases and the apoptosis-inducing factor PDCD8/AIF. Overexpression of this gene has been shown to induce apoptosis. The expression of this gene is found to be induced by tumor suppressor protein p53 in colon caner cells.
Alias Symbols: AMID, PRG3, RP11-367H5.2
Protein Interaction Partner: TP53, UBC, MYC,
Protein Size: 373

Molecular Weight: 40 kDa

Gene ID: 84883

NCBI Accession: NM_032797, NP_116186

UniProt: Q9BRQ8