AIFM2 antibody (Apoptosis-Inducing Factor, Mitochondrion-Associated, 2) (AA 319-348)

Details for Product anti-AIFM2 Antibody No. ABIN650623, Supplier: Log in to see
Antigen
  • im:6904058
  • AIFM2
  • AMID
  • DKFZp459F193
  • 5430437E11Rik
  • Amid
  • D730001I10Rik
  • PRG3
  • Prg3
  • RP11-367H5.2
  • apoptosis-inducing factor, mitochondrion-associated, 2
  • apoptosis inducing factor, mitochondria associated 2
  • apoptosis-inducing factor 2
  • apoptosis-inducing factor, mitochondrion-associated 2
  • apoptosis inducing factor, mitochondria associated 2 S homeolog
  • aifm2
  • AIFM2
  • SMAC_09295
  • Aifm2
  • aifm2.S
Epitope
AA 319-348, C-Term
15
9
4
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
Reactivity
Human
70
19
8
4
3
3
1
1
1
1
Host
Rabbit
47
15
9
Clonality (Clone)
Polyclonal ()
Conjugate
This AIFM2 antibody is un-conjugated
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
48
43
20
13
9
8
4
3
1
1
1
Options
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Immunogen This AIFM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 319-348 AA from the C-terminal region of human AIFM2.
Clone RB18257
Isotype Ig Fraction
Specificity This AIFM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 326~356 amino acids from the C-terminal region of human AIFM2.
Predicted Reactivity Cow (Bovine),Mouse (Murine)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Plasmids, Primers & others Plasmids, Primers & others AIFM2 products on genomics-online (e.g. as negative or positive controls)
Alternative Name AIFM2 (AIFM2 Antibody Abstract)
Background AIFM2 is significant homology to NADH oxidoreductases and the apoptosis-inducing factor PDCD8/AIF. The protein has been shown to induce apoptosis. This protein is found to be induced by tumor suppressor protein p53 in colon caner cells.
Synonyms: Apoptosis-inducing factor 2, Apoptosis-inducing factor-like mitochondrion-associated inducer of death, Apoptosis-inducing factor homologous mitochondrion-associated inducer of death, p53-responsive gene 3 protein , PRG3,
Synonyms: AMID, name: AIFM2
Molecular Weight 40527 DA
Gene ID 84883
UniProt Q9BRQ8
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 2 (AIFM2) (AA 319-348), (C-Term) antibody (ABIN650623) Western blot analysis of AIFM2 Antibody (C-term) (ABIN650623) in mouse liver tissue l...
Immunohistochemistry (IHC) image for anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 2 (AIFM2) (AA 319-348), (C-Term) antibody (ABIN650623) Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with AIFM2 Antibod...
Flow Cytometry (FACS) image for anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 2 (AIFM2) (AA 319-348), (C-Term) antibody (ABIN650623) AIFM2 Antibody (C-term) (ABIN650623) flow cytometric analysis of HepG2 cells (right h...
Background publications Wu, Xu, Su, Tian, Zhai, Shu: "AMID is a p53-inducible gene downregulated in tumors." in: Oncogene, Vol. 23, Issue 40, pp. 6815-9, 2004 (PubMed).

Ohiro, Garkavtsev, Kobayashi, Sreekumar, Nantz, Higashikubo, Duffy, Higashikubo, Usheva, Gius, Kley, Horikoshi: "A novel p53-inducible apoptogenic gene, PRG3, encodes a homologue of the apoptosis-inducing factor (AIF)." in: FEBS letters, Vol. 524, Issue 1-3, pp. 163-71, 2002 (PubMed).

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