AIFM2 antibody (Apoptosis-Inducing Factor, Mitochondrion-Associated, 2) (AA 319-348)

Details for Product anti-AIFM2 Antibody No. ABIN650623, Supplier: Log in to see
Antigen
  • im:6904058
  • AIFM2
  • AMID
  • DKFZp459F193
  • 5430437E11Rik
  • Amid
  • D730001I10Rik
  • PRG3
  • Prg3
  • RP11-367H5.2
  • apoptosis-inducing factor, mitochondrion-associated, 2
  • apoptosis inducing factor, mitochondria associated 2
  • apoptosis-inducing factor 2
  • apoptosis-inducing factor, mitochondrion-associated 2
  • apoptosis inducing factor, mitochondria associated 2 S homeolog
  • aifm2
  • AIFM2
  • SMAC_09295
  • Aifm2
  • aifm2.S
Epitope
AA 319-348, C-Term
15
9
4
4
3
3
3
3
2
2
2
2
2
2
1
1
1
1
Reactivity
Human
67
17
8
3
3
2
1
1
1
1
Host
Rabbit
43
15
10
Clonality (Clone)
Polyclonal ()
Conjugate
This AIFM2 antibody is un-conjugated
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
44
42
16
12
9
8
4
3
1
1
Options
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Immunogen This AIFM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 319-348 AA from the C-terminal region of human AIFM2.
Clone RB18257
Isotype Ig Fraction
Specificity This AIFM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 326~356 amino acids from the C-terminal region of human AIFM2.
Predicted Reactivity Cow (Bovine),Mouse (Murine)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name AIFM2 (AIFM2 Antibody Abstract)
Background AIFM2 is significant homology to NADH oxidoreductases and the apoptosis-inducing factor PDCD8/AIF. The protein has been shown to induce apoptosis. This protein is found to be induced by tumor suppressor protein p53 in colon caner cells.
Synonyms: Apoptosis-inducing factor 2, Apoptosis-inducing factor-like mitochondrion-associated inducer of death, Apoptosis-inducing factor homologous mitochondrion-associated inducer of death, p53-responsive gene 3 protein , PRG3,
Synonyms: AMID, name: AIFM2
Molecular Weight 40527 DA
Gene ID 84883
UniProt Q9BRQ8
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 2 (AIFM2) (AA 319-348), (C-Term) antibody (ABIN650623) Western blot analysis of AIFM2 Antibody (C-term) (ABIN650623) in mouse liver tissue l...
Immunohistochemistry (IHC) image for anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 2 (AIFM2) (AA 319-348), (C-Term) antibody (ABIN650623) Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with AIFM2 Antibod...
Flow Cytometry (FACS) image for anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 2 (AIFM2) (AA 319-348), (C-Term) antibody (ABIN650623) AIFM2 Antibody (C-term) (ABIN650623) flow cytometric analysis of HepG2 cells (right h...
Background publications Wu, Xu, Su, Tian, Zhai, Shu: "AMID is a p53-inducible gene downregulated in tumors." in: Oncogene, Vol. 23, Issue 40, pp. 6815-9, 2004 (PubMed).

Ohiro, Garkavtsev, Kobayashi, Sreekumar, Nantz, Higashikubo, Duffy, Higashikubo, Usheva, Gius, Kley, Horikoshi: "A novel p53-inducible apoptogenic gene, PRG3, encodes a homologue of the apoptosis-inducing factor (AIF)." in: FEBS letters, Vol. 524, Issue 1-3, pp. 163-71, 2002 (PubMed).

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