anti-IRF1 antibody (Interferon Regulatory Factor 1) (AA 216-325)

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Antigen
Synonyms irf1, zgc:136945, IRF1, irf11, zgc:103566, IRF-1, MAR, AU020929, Irf-1
Alternatives
Epitope
AA 216-325, partial
(22), (17), (16), (16), (5), (5), (5), (4), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(90), (27), (10), (4), (3), (2), (1), (1), (1)
Host
Mouse
(81), (21), (2), (2), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
This IRF1 antibody is un-conjugated
(6), (6), (4), (4), (4), (4), (1)
Application
ELISA, Western Blotting (WB)
(88), (44), (9), (8), (7), (6), (6), (5), (4), (3), (2), (1)
Pubmed 7 references available
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Quantity 100 μg
Shipping to United States ( )
Availability Will be delivered in 9 Business Day(s)
Immunogen IRF1 (NP_002189, 216 a.a. ~ 325 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen sequence: PMPSTSEATT DEDEEGKLPE DIMKLLEQSE WQPTNVDGKG YLLNEPGVQP TSVYGDFSCK EEPEIDSPGG DIGLSLQRVF TDLKNMDATW LDSLLTPVRL PSIQAIPCAP
Clone 2E4
Isotype IgG2a kappa
Cross-Reactivity Human
Alternative Name IRF1 (IRF1 Antibody Abstract)
Background Gene: interferon regulatory factor 1
Synonyms: IRF-1, MAR
Gene ID 3659
NCBI Accession NP_002189, NM_002198
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Pathways Interferon-gamma Pathway
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Buffer In 1x PBS, pH 7.4
Handling Advice Aliquot to avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Supplier Images
Western Blotting (WB) image for anti-IRF1 antibody (Interferon Regulatory Factor 1) (AA 216-325) (ABIN561520) IRF1 monoclonal antibody (M01), clone 2E4 Western Blot analysis of IRF1 expression in...
ELISA image for anti-IRF1 antibody (Interferon Regulatory Factor 1) (AA 216-325) (ABIN561520) Detection limit for recombinant GST tagged IRF1 is approximately 0.1ng/ml as a captur...
Image no. 3 for anti-IRF1 antibody (Interferon Regulatory Factor 1) (AA 216-325) (ABIN561520) Western Blot detection against Immunogen (37.84 KDa) .
Product cited in: Bartlett, Slater, Glanville et al.: "Defining critical roles for NF-?B p65 and type I interferon in innate immunity to rhinovirus." in: EMBO molecular medicine, Vol. 4, Issue 12, pp. 1244-60, 2012 (PubMed).

Baumjohann, Okada, Ansel: "Cutting Edge: Distinct waves of BCL6 expression during T follicular helper cell development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 5, pp. 2089-92, 2011 (PubMed).

Choi, Kageyama, Eto et al.: "ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6." in: Immunity, Vol. 34, Issue 6, pp. 932-46, 2011 (PubMed).

Nurieva, Chung, Martinez et al.: "Bcl6 mediates the development of T follicular helper cells." in: Science (New York, N.Y.), Vol. 325, Issue 5943, pp. 1001-5, 2009 (PubMed).

Fazilleau, McHeyzer-Williams, Rosen et al.: "The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding." in: Nature immunology, Vol. 10, Issue 4, pp. 375-84, 2009 (PubMed).

Steffen, MacKay, Kerr et al.: "Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4." in: Cell, Vol. 133, Issue 2, pp. 292-302, 2008 (PubMed).

Ye, Lista, Lo Coco et al.: "Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma." in: Science (New York, N.Y.), Vol. 262, Issue 5134, pp. 747-50, 1993 (PubMed).

Catalog No. ABIN561520
$430.00
Plus shipping costs $45.00 and $21.00 dry ice

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