Syndecan 1 (SDC1) (C-Term), (AA 266-295) antibody

Details for Product No. ABIN650771
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Antigen
Epitope
C-Term, AA 266-295
(13), (12), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(183), (34), (26), (13), (13), (12), (12), (5)
Host
Rabbit
(105), (75), (4), (2)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(14), (13), (7), (5), (5), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(82), (77), (62), (45), (29), (21), (15), (12), (10), (8), (6), (1), (1), (1), (1)
Pubmed 2 references available
Quantity 400 μL
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Catalog No. ABIN650771
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Immunogen This CD138 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-295 AA from the C-terminal region of human CD138.
Clone RB20734
Isotype Ig
Specificity This CD138 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273~303 amino acids from the C-terminal region of human CD138.
Predicted Reactivity Cow (Bovine),Hamster,Mouse (Murine),Rat (Rattus)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name CD138
Background CD138 is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins.
Synonyms: Syndecan-1, SYND1, CD_antigen=CD138, Flags: Precursor, SDC, SDC1
Molecular Weight 32462 DA
Gene ID 6382
UniProt P18827
Research Area Stem Cells
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Syndecan 1 (SDC1) (C-Term), (AA 266-295) antibody Western blot analysis of CD138 Antibody (C-term K281) (ABIN650771) in HepG2 cell line lysates (35 µg/lane). CD138 (arrow) was detected using the purified polyclonal antibody.
Background publications Rikova, Guo, Zeng et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. ..." in: Cell, Vol. 131, Issue 6, pp. 1190-203, 2007 (PubMed).

Endo, Takino, Miyamori et al.: "Cleavage of syndecan-1 by membrane type matrix metalloproteinase-1 stimulates cell migration." in: The Journal of biological chemistry, Vol. 278, Issue 42, pp. 40764-70, 2003 (PubMed).

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