Activating Transcription Factor 1 (AFT1) (C-Term), (AA 193-219) antibody

Details for Product No. ABIN651055
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Antigen
Synonyms ews-atf1, fus/atf-1, treb36, ATF1, EWS-ATF1, FUS/ATF-1, TREB36, Atf-1, wu:fc92c07, zgc:64099
Epitope
C-Term, AA 193-219
(26), (13), (5), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(99), (61), (32), (4), (3), (2), (2), (2), (1), (1)
Host
Rabbit
(90), (8), (2), (2)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application
Western Blotting (WB), Flow Cytometry (FACS)
(81), (43), (20), (18), (14), (11), (8), (6), (6), (3), (2), (1)
Pubmed 2 references available
Quantity 400 μL
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Catalog No. ABIN651055
291.50 $
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Immunogen This ATF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-219 AA from the C-terminal region of human ATF1.
Clone RB22228
Isotype Ig
Specificity This ATF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ATF1.
Predicted Reactivity Cow (Bovine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ATF1
Background ATF1 binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. ATF1 binds to the Tax-responsive element (TRE) of HTLV-I. ATF1 mediates PKA-induced stimulation of CRE-reporter genes.
Synonyms: Protein TREB36, Activating transcription factor 1, Cyclic AMP-dependent transcription factor ATF-1, cAMP-dependent transcription factor ATF-1,ATF1
Molecular Weight 29233 DA
Gene ID 466
UniProt P18846
Research Area Translation Factors, Phospho-specific antibodies, Protein Modifications, Cancer, Transcription Factors, Chromatin, Signaling, Cell Structure
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Activating Transcription Factor 1 (AFT1) (C-Term), (AA 193-219) antibody Western blot analysis of ATF1 Antibody (C-term) (ABIN651055) in Jurkat cell line lysates (35 µg/lane). ATF1 (arrow) was detected using the purified polyclonal antibody.
anti-Activating Transcription Factor 1 (AFT1) (C-Term), (AA 193-219) antibody (2) ATF1 Antibody (C-term) (ABIN651055) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications Zheng, Cho, Lau et al.: "Cyclin-dependent kinase 3-mediated activating transcription factor 1 phosphorylation enhances cell transformation." in: Cancer research, Vol. 68, Issue 18, pp. 7650-60, 2008 (PubMed).

Vega, Salas, Milne et al.: "Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study." in: Gynecologic oncology, Vol. 112, Issue 1, pp. 210-4, 2008 (PubMed).

Validation Images
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