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Details for Product No. ABIN651055

Activating Transcription Factor 1 (AFT1) (C-Term), (AA 193-219) antibody

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Antigen
Synonyms TREB36, EWS-ATF1, FUS/ATF-1, Atf-1, zgc:64099, wu:fc92c07, ews-atf1, fus/atf-1, treb36, ATF1
Epitope
»Alternatives C-Term, AA 193-219
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Flow Cytometry (FACS)
Pubmed 2 references available
Catalog no. ABIN651055
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This ATF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-219 AA from the C-terminal region of human ATF1.
Clone RB22228
Isotype Ig
Specificity This ATF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ATF1.
Predicted Reactivity Cow (Bovine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ATF1
Background ATF1 binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. ATF1 binds to the Tax-responsive element (TRE) of HTLV-I. ATF1 mediates PKA-induced stimulation of CRE-reporter genes.
Synonyms: Protein TREB36, Activating transcription factor 1, Cyclic AMP-dependent transcription factor ATF-1, cAMP-dependent transcription factor ATF-1,ATF1
Molecular Weight 29233 DA
Gene ID 466
UniProt P18846
Research Area Translation Factors, Phospho-specific antibodies, Protein Modifications, Cancer, Transcription Factors, Chromatin, Signaling, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,FC : 1:10-50
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Zheng, Cho, Lau et al.: "Cyclin-dependent kinase 3-mediated activating transcription factor 1 phosphorylation enhances cell transformation." in: Cancer research, Vol. 68, Issue 18, pp. 7650-60, 2008 (PubMed).

Vega, Salas, Milne et al.: "Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study." in: Gynecologic oncology, Vol. 112, Issue 1, pp. 210-4, 2008 (PubMed).

Alternatives for antigen "Activating Transcription Factor 1 (AFT1)", type "Antibodies"
Hosts (65), (9), (4), (1)
Reactivities (75), (54), (29), (4), (3), (3), (2), (2), (2), (1)
Applications (60), (36), (20), (16), (8), (8), (4), (2), (2), (2), (1), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (22), (5), (5), (3), (3), (1), (1), (1), (1), (1), (1)
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