AFT1 antibody (AA 1-210)

Catalog No. ABIN7148788

Product Details anti-AFT1 Antibody

Target: AFT1 (Activating Transcription Factor 1 (AFT1))

Binding Specificity: AA 1-210

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AFT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Cyclic AMP-dependent transcription factor ATF-1 protein (1-210AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for AFT1

Target: AFT1 (Activating Transcription Factor 1 (AFT1))

Alternative Name: ATF1 (AFT1 Products)

Synonyms: ews-atf1 antibody, fus/atf-1 antibody, treb36 antibody, ATF1 antibody, EWS-ATF1 antibody, FUS/ATF-1 antibody, TREB36 antibody, Atf-1 antibody, wu:fc92c07 antibody, zgc:64099 antibody, activating transcription factor 1 antibody, activating transcription factor 1 L homeolog antibody, atf1 antibody, ATF1 antibody, MGC85066 antibody, atf1.L antibody, Atf1 antibody

Background:

Background: This protein binds the cAMP response element (CRE) (consensus: 5\\\'-GTGACGT[AC][AG]-3\\\'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.

Aliases: Activating transcription factor 1 antibody, ATF 1 antibody, atf1 antibody, ATF1 EWS fusion gene antibody, ATF1 FUS fusion gene antibody, ATF1_HUMAN antibody, cAMP dependent transcription factor 1 antibody, cAMP-dependent transcription factor ATF-1 antibody, Cyclic AMP dependent transcription factor ATF 1 antibody, Cyclic AMP dependent transcription factor ATF1 antibody, Cyclic AMP-dependent transcription factor ATF-1 antibody, EWS AFT1 antibody, FUS ATF 1 antibody, FUS/ATF 1 antibody, Protein TREB36 antibody, RNA binding protein activating transcription factor 1 fusion protein antibody, TREB 36 antibody, TREB36 antibody, TREB36 protein antibody

UniProt: P18846

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades