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Details for Product No. ABIN651123

Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 217-245), (Center) antibody

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Antigen
Synonyms CD64, CD64A, FCRI, IGFR1, FCGR1A, FcgammaRI, Fcgr1, Fcgr1b
Epitope
»Alternatives AA 217-245, Center
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
Pubmed 3 references available
Catalog no. ABIN651123
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This FCGR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-245 AA from the Central region of human FCGR1A.
Clone RB24072
Isotype Ig
Specificity This FCGR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between amino acid 225-255 from the Central region of human FCGR1A.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name FCGR1A
Background FCGR1A encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1.
Synonyms: CD_antigen=CD64, Flags: Precursor, Fc-gamma RI, FcRI, Fc-gamma RIA, FcgammaRIa, High affinity immunoglobulin gamma Fc receptor I, IgG Fc receptor I,IGFR1, FCGR1, FCG1, FCGR1A
Molecular Weight 42632 DA
Gene ID 2209
UniProt P12314
Research Area Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Poon, Hulett, Parish: "Histidine-rich glycoprotein is a novel plasma pattern recognition molecule that recruits IgG to facilitate necrotic cell clearance via FcgammaRI on phagocytes." in: Blood, Vol. 115, Issue 12, pp. 2473-82, 2010 (PubMed).

Jung, Reddy, Kang et al.: "Aglycosylated IgG variants expressed in bacteria that selectively bind FcgammaRI potentiate tumor cell killing by monocyte-dendritic cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 2, pp. 604-9, 2010 (PubMed).

Hulse, Reefer, Engelhard et al.: "Targeting allergen to FcgammaRI reveals a novel T(H)2 regulatory pathway linked to thymic stromal lymphopoietin receptor." in: The Journal of allergy and clinical immunology, Vol. 125, Issue 1, pp. 247-56.e1-8, 2010 (PubMed).

Alternatives for antigen "Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A)", type "Antibodies"
Hosts (96), (22)
Reactivities (114), (18), (15), (15), (12), (12), (8), (1)
Applications (89), (50), (19), (19), (17), (15), (14), (14), (10), (10), (10), (9), (7), (4), (1), (1), (1)
Conjugates (18), (16), (9), (6), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (2), (2), (1), (1), (1), (1)
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