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Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 217-245), (Center) antibody

Details for Product No. ABIN651123, Supplier: Login to see
Antigen
  • CD64
  • CD64A
  • FCRI
  • IGFR1
  • FcgammaRI
  • Fcgr1
  • Fcgr1b
  • AI323638
  • AV092959
  • IGGHAFC
  • FCGR1A
Epitope
AA 217-245, Center
14
13
13
7
4
3
3
2
2
2
1
1
1
1
1
Reactivity
Human
218
33
17
13
8
7
7
6
Host
Rabbit
179
52
2
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
35
32
16
10
4
4
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
172
87
42
40
28
27
26
22
22
15
11
8
7
4
2
2
2
2
1
Supplier
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Immunogen This FCGR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-245 AA from the Central region of human FCGR1A.
Clone RB24072
Isotype Ig
Specificity This FCGR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between amino acid 225-255 from the Central region of human FCGR1A.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name FCGR1A (FCGR1A Antibody Abstract)
Background FCGR1A encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1.
Synonyms: CD_antigen=CD64, Flags: Precursor, Fc-gamma RI, FcRI, Fc-gamma RIA, FcgammaRIa, High affinity immunoglobulin gamma Fc receptor I, IgG Fc receptor I,IGFR1, FCGR1, FCG1, FCGR1A
Molecular Weight 42632 DA
Gene ID 2209
UniProt P12314
Research Area Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications
Pathways
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 217-245), (Center) antibody (ABIN651123) Western blot analysis of FCGR1A Antibody (Center) (ABIN651123) in NCI-H460 cell line ...
Immunohistochemistry (IHC) image for anti-Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 217-245), (Center) antibody (ABIN651123) FCGR1A Antibody (Center) (ABIN651123) IHC analysis in formalin fixed and paraffin emb...
Flow Cytometry (FACS) image for anti-Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 217-245), (Center) antibody (ABIN651123) FCGR1A Antibody (Center) (ABIN651123) flow cytometric analysis of NCI-H460 cells (rig...
Background publications Hulse, Reefer, Engelhard et al.: "Targeting allergen to FcgammaRI reveals a novel T(H)2 regulatory pathway linked to thymic stromal lymphopoietin receptor." in: The Journal of allergy and clinical immunology, Vol. 125, Issue 1, pp. 247-56.e1-8, 2010 (PubMed).

Jung, Reddy, Kang et al.: "Aglycosylated IgG variants expressed in bacteria that selectively bind FcgammaRI potentiate tumor cell killing by monocyte-dendritic cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 2, pp. 604-9, 2010 (PubMed).

Poon, Hulett, Parish: "Histidine-rich glycoprotein is a novel plasma pattern recognition molecule that recruits IgG to facilitate necrotic cell clearance via FcgammaRI on phagocytes." in: Blood, Vol. 115, Issue 12, pp. 2473-82, 2010 (PubMed).