N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 2 (NDST2) (AA 817-844), (C-Term) antibody

Details for Product No. ABIN651945
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Antigen
Epitope
AA 817-844, C-Term
(15), (15), (1)
Reactivity
Human, Mouse (Murine)
(19), (1)
Host
Rabbit
(19)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB)
(17), (13), (3), (1)
Pubmed 4 references available
Quantity 400 μL
Options
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Immunogen This NDST2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 817-844 AA from the C-terminal region of human NDST2.
Clone RB21472
Isotype Ig
Specificity This NDST2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 824-853 amino acids from the C-terminal region of human NDST2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name NDST2 (NDST2 Antibody Abstract)
Background NDST2 is a member of the N-deacetylase/N-sulfotransferase subfamily of the sulfotransferase 1 proteins. The encoded enzyme has dual functions in processing glucosamine and heparin polymers, including N-deacetylation and N-sulfation. The encoded protein may be localized to the Golgi.
Synonyms: Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2,NDST2,HSST2
Molecular Weight 100875 DA
Gene ID 8509
NCBI Accession NP_003626
UniProt P52849
Research Area Cell Signaling, Protein Modifications, Cell Structure, Metabolism
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 2 (NDST2) (AA 817-844), (C-Term) antibody NDST2 Antibody (C-term) (ABIN651945) western blot analysis in mouse cerebellum tissue...
Product cited in: Gasimli, Glass, Datta et al.: "Bioengineering murine mastocytoma cells to produce anticoagulant heparin." in: Glycobiology, Vol. 24, Issue 3, pp. 272-80, 2014 (PubMed).

Datta, Li, Yang et al.: "Bioengineered Chinese hamster ovary cells with Golgi-targeted 3-O-sulfotransferase-1 biosynthesize heparan sulfate with an antithrombin-binding site." in: The Journal of biological chemistry, Vol. 288, Issue 52, pp. 37308-18, 2013 (PubMed).

Background publications Grupe, Li, Rowland et al.: "A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. ..." in: American journal of human genetics, Vol. 78, Issue 1, pp. 78-88, 2005 (PubMed).

Duncan, Liu, Fox et al.: "Characterization of the N-deacetylase domain from the heparan sulfate N-deacetylase/N-sulfotransferase 2." in: Biochemical and biophysical research communications, Vol. 339, Issue 4, pp. 1232-7, 2005 (PubMed).

Validation Images
Catalog No. ABIN651945
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