NDST2 antibody (N-Term)

Catalog No. ABIN6992024

Product Details anti-NDST2 Antibody

Target: NDST2 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 2 (NDST2))

Binding Specificity: AA 20-70, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDST2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificity: NDST2 antibody is human, mouse and rat reactive. At least two isoforms of NDST2 are known to exist, this antibody will only detect the larger isoform. NDST2 antibody is predicted not to cross-react with other members of the NDST protein family.

Purification: NDST2 antibody is affinity chromatography purified via peptide column.

Immunogen: NDST2 antibody was raised against a 16 amino acid peptide near the amino terminus of human NDST2. The immunogen is located within amino acids 20 - 70 of NDST2.

Isotype: IgG

Application Details

Application Notes: NDST2 antibody can be used for detection of PDCL by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: NDST2 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: NDST2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for NDST2

Target: NDST2 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 2 (NDST2))

Alternative Name: NDST2 (NDST2 Products)

Synonyms: NDST1 antibody, HSST2 antibody, NST2 antibody, Mndns antibody, NDST-2 antibody, ndst2 antibody, N-deacetylase and N-sulfotransferase 2 antibody, N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 antibody, N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2b antibody, NDST2 antibody, Ndst2 antibody, ndst2b antibody

Background: The N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 (NDST2) protein, also known as N-heparan sulfate sulfotransferase 2, and the highly related protein NDST1 have key roles in the sulfation of heparan sulfate proteoglycans, molecules that are present of cell surfaces and the extracellular matrix (1,2). NDST1 and NDST2 are dispensable for mesodermal differentiation into osteoblasts but necessary for induction of adipocytes and neural cells (3).

Molecular Weight: Predicted: 97 kDa

Observed: 101 kDa

Gene ID: 8509

NCBI Accession: NP_003626

UniProt: P52849

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Glycosaminoglycan Metabolic Process