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Details for Product No. ABIN652928

Spindle and Kinetochore Associated Complex Subunit 3 (SKA3) (AA 226-253), (Center) antibody

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Antigen
Synonyms C13orf3, RAMA1, RGD1307201, C12H13ORF3, F630043A04Rik, rama1, fc23d11, wu:fc23d11, si:rp71-68n21.13
Epitope
»Alternatives AA 226-253, Center
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
Pubmed 1 reference available
Catalog no. ABIN652928
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This C13orf3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-253 AA from the Central region of human C13orf3.
Clone RB23058
Isotype Ig
Specificity This C13orf3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232~262 amino acids from the Center region of human C13orf3.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name C13orf3
Background Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the microtubule-stimulated oligomerization.
Synonyms: Spindle and kinetochore-associated protein 3, SKA3, C13orf3, RAMA1
Molecular Weight 46359 DA
Gene ID 221150
UniProt Q8IX90
Research Area Cancer, Cell Cycle, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100,FC : 1:10-50
Restrictions For Research Use only
Concentration 0.36 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Rush, Moritz, Lee et al.: "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells." in: Nature biotechnology, Vol. 23, Issue 1, pp. 94-101, 2005 (PubMed).

Alternatives for antigen "Spindle and Kinetochore Associated Complex Subunit 3 (SKA3)", type "Antibodies"
Hosts (25), (3)
Reactivities (27), (20), (20), (11), (11), (2)
Applications (17), (14), (9), (8), (3), (2)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (8), (5), (1), (1), (1)
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