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Details for Product No. ABIN653225

Xanthine Dehydrogenase (XDH) (N-Term), (AA 206-234) antibody

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Antigen
Synonyms XO, XOR, Xor, Xox1, Xox-1, XDH, im:7146167, DDBDRAFT_0219626, DDBDRAFT_0230176, DDB_0219626, DDB_0230176
Epitope
»Alternatives N-Term, AA 206-234
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
Pubmed 2 references available
Catalog no. ABIN653225
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This XDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-234 AA from the N-terminal region of human XDH.
Clone RB23202
Isotype Ig
Specificity This XDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213~242 amino acids from the N-terminal region of human XDH.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name XDH
Background XDH belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The enzyme is a homodimer. This protein can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.
Synonyms: Xanthine oxidoreductase, Xanthine oxidase, XO, Xanthine dehydrogenase, XD, Xanthine dehydrogenase/oxidase, XDHA, XDH
Molecular Weight 146424 DA
Gene ID 7498
UniProt P47989
Research Area Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.38 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Taibi, Carruba, Miceli et al.: "Estradiol decreases xanthine dehydrogenase enzyme activity and protein expression in non-tumorigenic and malignant human mammary epithelial cells." in: Journal of cellular biochemistry, Vol. 108, Issue 3, pp. 688-92, 2009 (PubMed).

Ross, Katzov-Eckert, Dubé et al.: "Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy." in: Nature genetics, Vol. 41, Issue 12, pp. 1345-9, 2009 (PubMed).

Alternatives for antigen "Xanthine Dehydrogenase (XDH)", type "Antibodies"
Hosts (55), (3)
Reactivities (52), (21), (20), (17), (13), (1), (1), (1), (1), (1)
Applications (46), (39), (20), (11), (10), (9), (8), (2), (2), (2), (1), (1), (1), (1), (1)
Conjugates (9), (7), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (2), (1)
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