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alpha 1b Adrenergic Receptor antibody (Adrenergic, alpha-1B-, Receptor) (AA 270-297)

Details for Product anti-ADRA1B Antibody No. ABIN653353, Supplier: Log in to see
Antigen
  • LOC100136712
  • [a]1b
  • ADRA1
  • ALPHA1BAR
  • RDC5
Alternatives
anti-Human alpha 1b Adrenergic Receptor antibody for Immunohistochemistry (Paraffin-embedded Sections)
Epitope
AA 270-297, Center
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25
17
16
10
10
5
5
3
2
2
2
1
1
1
1
Reactivity
Human
121
38
35
4
4
4
2
1
1
1
1
Host
Rabbit
107
13
1
Clonality (Clone)
Polyclonal ()
Conjugate
This alpha 1b Adrenergic Receptor antibody is un-conjugated
6
6
6
5
5
5
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
77
62
29
20
11
9
3
3
2
Supplier
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Immunogen This ADRA1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-297 AA from the Central region of human ADRA1B.
Clone RB25170
Isotype Ig
Specificity This ADRA1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 276~306 amino acids from the Central region of human ADRA1B.
Predicted Reactivity Cow (Bovine),Mouse (Murine),Rat (Rattus),Rabbit
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ADRA1B (ADRA1B Antibody Abstract)
Background Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This protein encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This protein comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.
Synonyms: Alpha-1B adrenergic receptor, Alpha-1B adrenoreceptor, ADRA1B
Molecular Weight 56,836 DA
Gene ID 147
UniProt P35368
Research Area Cell Structure
Pathways AMPK Signaling
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-alpha 1b Adrenergic Receptor antibody (Adrenergic, alpha-1B-, Receptor) (AA 270-297) (ABIN653353) Western blot analysis of ADRA1B Antibody (Center) (ABIN653353) in NCI-H460 cell line ...
Immunohistochemistry (IHC) image for anti-alpha 1b Adrenergic Receptor antibody (Adrenergic, alpha-1B-, Receptor) (AA 270-297) (ABIN653353) Formalin-fixed and paraffin-embedded human brain with ADRA1B Antibody (Center), which...
Background publications Mathias, Grant, Rafaels et al.: "A genome-wide association study on African-ancestry populations for asthma." in: The Journal of allergy and clinical immunology, Vol. 125, Issue 2, pp. 336-346.e4, 2010 (PubMed).