Adrenergic, alpha-1B-, Receptor (ADRA1B) (AA 270-297), (Center) antibody

Details for Product No. ABIN653353
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Antigen
Synonyms ADRA1, ALPHA1BAR, RDC5, LOC100136712
Epitope
AA 270-297, Center
(12), (5), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(64), (27), (25), (14), (14), (13), (12), (12), (1)
Host
Rabbit
(61), (4), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(31), (23), (23), (10), (8), (5), (4), (3), (2), (1)
Pubmed 1 reference available
Catalog no. ABIN653353
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This ADRA1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-297 AA from the Central region of human ADRA1B.
Clone RB25170
Isotype Ig
Specificity This ADRA1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 276~306 amino acids from the Central region of human ADRA1B.
Predicted Reactivity Cow (Bovine),Mouse (Murine),Rat (Rattus),Rabbit
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ADRA1B
Background Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This protein encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This protein comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.
Synonyms: Alpha-1B adrenergic receptor, Alpha-1B adrenoreceptor, ADRA1B
Molecular Weight 56,836 DA
Gene ID 147
UniProt P35368
Research Area Cell Structure
Application Notes WB = 1:1000, IHC = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Adrenergic, alpha-1B-, Receptor (ADRA1B) (AA 270-297), (Center) antibody Western blot analysis of ADRA1B Antibody (Center) (ABIN653353) in NCI-H460 cell line lysates (35 µg/lane). ADRA1B (arrow) was detected using the purified polyclonal antibody.
anti-Adrenergic, alpha-1B-, Receptor (ADRA1B) (AA 270-297), (Center) antibody (2) Formalin-fixed and paraffin-embedded human brain with ADRA1B Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Background publications Mathias, Grant, Rafaels et al.: "A genome-wide association study on African-ancestry populations for asthma." in: The Journal of allergy and clinical immunology, Vol. 125, Issue 2, pp. 336-346.e4, 2010 (PubMed).

Hosts (61), (4), (1)
Reactivities (64), (27), (25), (14), (14), (13), (12), (12), (1)
Applications (31), (23), (23), (10), (8), (5), (4), (3), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (12), (5), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
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