Lecithin-Cholesterol Acyltransferase (LCAT) (AA 285-313), (Center) antibody

Details for Product No. ABIN653825
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Antigen
Synonyms AI046659, D8Wsu61e, MGC82035, lcat, MGC88964, LCAT
Epitope
AA 285-313, Center
(6), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(43), (25), (24), (14), (13), (13), (1)
Host
Rabbit
(52), (4)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(7), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
(46), (25), (14), (10), (10), (9), (9), (5), (3), (1), (1), (1)
Pubmed 3 references available
Catalog no. ABIN653825
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This LCAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 285-313 AA from the Central region of human LCAT.
Clone RB23365
Isotype Ig
Specificity This LCAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292~321 amino acids from the Central region of human LCAT.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name LCAT
Background LCAT encodes the extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. The esterification of cholesterol is required for cholesterol transport.
Synonyms: Phospholipid-cholesterol acyltransferase, Lecithin-cholesterol acyltransferase, Phosphatidylcholine-sterol acyltransferase,LCAT
Pathways: Glycerophospholipid metabolism
Molecular Weight 49578 Da
Gene ID 3931
UniProt P04180
Research Area Signaling, Cell Signaling, Protein Modifications, Metabolism, Cell Structure
Application Notes WB = 1:1000, IHC = 1:10-50, IF = 1:10-50, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.39 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Lecithin-Cholesterol Acyltransferase (LCAT) (AA 285-313), (Center) antibody Western blot analysis of LCAT Antibody (Center) (ABIN653825) in K562 cell line lysates (35 µg/lane). LCAT (arrow) was detected using the purified polyclonal antibody.
anti-Lecithin-Cholesterol Acyltransferase (LCAT) (AA 285-313), (Center) antibody (2) LCAT Antibody (Center) (ABIN653825) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining
anti-Lecithin-Cholesterol Acyltransferase (LCAT) (AA 285-313), (Center) antibody (3) LCAT Antibody (Center) (ABIN653825) flow cytometric analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications McGeachie, Ramoni, Mychaleckyj et al.: "Integrative predictive model of coronary artery calcification in atherosclerosis." in: Circulation, Vol. 120, Issue 24, pp. 2448-54, 2009 (PubMed).

Voora, Shah, Reed et al.: "Pharmacogenetic predictors of statin-mediated low-density lipoprotein cholesterol reduction and dose response." in: Circulation. Cardiovascular genetics, Vol. 1, Issue 2, pp. 100-6, 2009 (PubMed).

Weissglas-Volkov, Aguilar-Salinas, Sinsheimer et al.: "Investigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples." in: Circulation. Cardiovascular genetics, Vol. 3, Issue 1, pp. 31-8, 2010 (PubMed).

Hosts (52), (4)
Reactivities (43), (25), (24), (14), (13), (13), (1)
Applications (46), (25), (14), (10), (10), (9), (9), (5), (3), (1), (1), (1)
Conjugates (7), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
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