Holocytochrome C Synthase (HCCS) (AA 173-200), (Center) antibody

Details for Product No. ABIN653839
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Antigen
Synonyms hccsb, id:ibd1278, wu:fb18h01, wu:fc64e12, wu:fi43e01, cchl, mcops7, DDBDRAFT_0217711, DDBDRAFT_0266707, DDB_0217711, DDB_0266707, CCHL, MCOPS7, RGD1563855
Epitope
AA 173-200, Center
(8), (3), (3), (3), (3), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(52), (27), (15), (12), (1)
Host
Rabbit
(45), (8)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(42), (22), (22), (11), (10), (6), (5), (3), (2), (1), (1)
Pubmed 2 references available
Quantity 400 μL
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Catalog No. ABIN653839
291.50 $
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Immunogen This HCCS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 173-200 AA from the Central region of human HCCS.
Clone RB24043
Isotype Ig
Specificity This HCCS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179~209 amino acids from the Central region of human HCCS.
Predicted Reactivity Cow (Bovine),Chicken
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name HCCS
Background The protein encoded by this gene is an enzyme that covalently links a heme group to the apoprotein of cytochrome c. Defects in this gene are a cause of microphthalmia syndromic type 7 (MCOPS7). Three transcript variants encoding the same protein have been found for this gene.
Synonyms: Holocytochrome c-type synthase, Cytochrome c-type heme lyase, CCHL,CCHL, HCCS
Molecular Weight 30602 DA
Gene ID 3052
UniProt P53701
Research Area Cell Structure, Cancer
Application Notes WB = 1:1000, IHC = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Holocytochrome C Synthase (HCCS) (AA 173-200), (Center) antibody Western blot analysis of HCCS Antibody (Center) (ABIN653839) in WiDr cell line lysates (35 µg/lane). HCCS (arrow) was detected using the purified polyclonal antibody.
anti-Holocytochrome C Synthase (HCCS) (AA 173-200), (Center) antibody (2) Western blot analysis of HCCS Antibody (Center) (ABIN653839) in mouse heart tissue lysates (35 µg/lane). HCCS (arrow) was detected using the purified polyclonal antibody.
anti-Holocytochrome C Synthase (HCCS) (AA 173-200), (Center) antibody (3) HCCS Antibody (Center) (ABIN653839) IHC analysis in formalin fixed and paraffin embedded colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining
Background publications Nakashima-Kamimura, Asoh, Ishibashi et al.: "MIDAS/GPP34, a nuclear gene product, regulates total mitochondrial mass in response to mitochondrial dysfunction." in: Journal of cell science, Vol. 118, Issue Pt 22, pp. 5357-67, 2005 (PubMed).

Need, Attix, McEvoy et al.: "A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB." in: Human molecular genetics, Vol. 18, Issue 23, pp. 4650-61, 2009 (PubMed).

Validation Images
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