The Rabbit Polyclonal anti-HCCS antibody (ABIN952686) specifically detects HCCS in WB and IHC (p).
The antibody is reactive with Human and Mouse samples.
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
HCCS
(Holocytochrome C Synthase (HCCS))
Alternative Name
HCCS / CCHL
Background
The protein encoded by this gene is an enzyme that covalently links a heme group to the apoprotein of cytochrome c. Defects in this gene are a cause of microphthalmia syndromic type 7 (MCOPS7). Three transcript variants encoding the same protein have been found for this gene.Synonyms: Cytochrome c-type heme lyase, Holocytochrome c-type synthase