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Details for Product No. ABIN654229

Transcription Factor A, Mitochondrial (TFAM) (C-Term), (AA 216-246) antibody

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Antigen
Synonyms Hmgts, mtTFA, tsHMG, AI661103, Mttfa, MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3, tcf6, mttf1, mttfa, tcf6l1, tcf6l2, tcf6l3, mttfa-A, xl-mtTFA, MGC153358, zgc:153358
Epitope
»Alternatives C-Term, AA 216-246
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN654229
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This TFAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 216-246 AA from the C-terminal region of human TFAM.
Clone RB27631
Isotype Ig
Specificity This TFAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-254 amino acids from the C-terminal region of human TFAM.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name TFAM
Background This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells.
Synonyms: Transcription factor A, mitochondrial,TFAM,TCF6, TCF6L2
Molecular Weight 29097 DA
Gene ID 7019
UniProt Q00059, NP_003192.1
Research Area Translation Factors, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Transcription Factors, Signaling, Cell Structure
Application Notes Recommend dilutions: IHC : 1:50-100,FC : 1:10-50,IF : 1:10-50,WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Shulman, Chibnik, Aubin et al.: "Intermediate phenotypes identify divergent pathways to Alzheimer's disease." in: PLoS ONE, Vol. 5, Issue 6, pp. e11244, 2010 (PubMed).

Alternatives for antigen "Transcription Factor A, Mitochondrial (TFAM)", type "Antibodies"
Hosts (50), (2)
Reactivities (43), (20), (19), (14), (13), (13)
Applications (34), (15), (14), (13), (13), (10), (6), (3), (3), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (5), (3), (3), (2), (2), (2), (1)
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