Angiopoietin 1 (ANGPT1) (C-Term), (AA 374-402) antibody

Details for Product No. ABIN654409
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Antigen
Synonyms ang1, wu:fc76g06, ANG-1, angpt1, MGC80788, 1110046O21Rik, Ang-1, Ang1, AGP1, AGPT, ANG1, Agpt, Agpt1, DHCR14A, NET47
Epitope
C-Term, AA 374-402
(13), (10), (8), (7), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(64), (40), (20), (18), (12), (12), (2)
Host
Rabbit
(77), (5), (4), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(9), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(71), (45), (23), (19), (11), (11), (10), (2), (1)
Pubmed 3 references available
Quantity 400 µL
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Catalog No. ABIN654409
291.50 $
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Immunogen This ANGPT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-402 AA from the C-terminal region of human ANGPT1.
Clone RB17673
Isotype Ig
Specificity This ANGPT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-410 amino acids from the C-terminal region of human ANGPT1.
Predicted Reactivity Cow (Bovine),Mouse (Murine),Pig (Porcine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ANGPT1
Background Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart.
Synonyms: ANGPT1,Angiopoietin-1,KIAA0003
Molecular Weight 57513 DA
Gene ID 284
NCBI Accession NP_001137
UniProt Q15389
Research Area Cell Signaling, Protein Modifications, Cell Cycle, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.36 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Angiopoietin 1 (ANGPT1) (C-Term), (AA 374-402) antibody ANGPT1 Antibody (C-term) (ABIN654409) western blot analysis in NCI-H292 cell line lysates (35 µg/lane). This demonstrates the ANGPT1 antibody detected the ANGPT1 protein (arrow).
Background publications Chen, Yang, Yu et al.: "A functional variant in the 3'-UTR of angiopoietin-1 might reduce stroke risk by interfering with the binding efficiency of microRNA 211." in: Human molecular genetics, Vol. 19, Issue 12, pp. 2524-33, 2010 (PubMed).

Fang, Neyrinck, Matthay et al.: "Allogeneic human mesenchymal stem cells restore epithelial protein permeability in cultured human alveolar type II cells by secretion of angiopoietin-1." in: The Journal of biological chemistry, Vol. 285, Issue 34, pp. 26211-22, 2010 (PubMed).

Ruaño, Thompson, Kane et al.: "Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?" in: Pharmacogenomics, Vol. 11, Issue 7, pp. 959-71, 2010 (PubMed).

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