Activating Transcription Factor 7 Interacting Protein 2 (ATF7IP2) (AA 318-347), (Center) antibody

Details for Product No. ABIN654466
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

 
Antigen
Synonyms MCAF2, 4930558K11Rik, BC018510, Get-1, PSM2
Epitope
AA 318-347, Center
(2), (2), (1), (1)
Reactivity
Human, Mouse (Murine)
(5), (2)
Host
Rabbit
(5)
Clonality (Clone)
Polyclonal ()
Application
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
(5), (3), (2), (1), (1)
Pubmed 1 reference available
Catalog no. ABIN654466
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
Options
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This MCAF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-347 AA from the Central region of human MCAF2.
Clone RB28618
Isotype Ig
Specificity This MCAF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-355 amino acids from the Central region of human MCAF2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name MCAF2
Background Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone 'Lys-9' trimethylation activity (Probable).
Synonyms: ATF7IP2,Activating transcription factor 7-interacting protein 2,MCAF2
Molecular Weight 75764 DA
Gene ID 80063
UniProt Q5U623, NP_079273.2
Research Area Translation Factors, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Signaling, Cell Structure
Application Notes WB = 1:1000, IHC = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Activating Transcription Factor 7 Interacting Protein 2 (ATF7IP2) (AA 318-347), (Center) antibody MCAF2 Antibody (Center) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the MCAF2 antibody detected the MCAF2 protein (arrow).
anti-Activating Transcription Factor 7 Interacting Protein 2 (ATF7IP2) (AA 318-347), (Center) antibody (2) MCAF2 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the MCAF2 antibody detected the MCAF2 protein (arrow).
anti-Activating Transcription Factor 7 Interacting Protein 2 (ATF7IP2) (AA 318-347), (Center) antibody (3) MCAF2 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MCAF2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
anti-Activating Transcription Factor 7 Interacting Protein 2 (ATF7IP2) (AA 318-347), (Center) antibody (4) MCAF2 Antibody (Center) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications Ichimura, Watanabe, Sakamoto et al.: "Transcriptional repression and heterochromatin formation by MBD1 and MCAF/AM family proteins." in: The Journal of biological chemistry, Vol. 280, Issue 14, pp. 13928-35, 2005 (PubMed).

Hosts (5)
Reactivities (5), (2)
Applications (5), (3), (2), (1), (1)
Epitopes (2), (2), (1), (1)
back to top