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Activating Transcription Factor 7 Interacting Protein 2 (ATF7IP2) (AA 318-347), (Center) antibody

Details for Product No. ABIN654466, Supplier: Log in to see
Antigen
  • MCAF2
  • 4930558K11Rik
  • BC018510
  • Get-1
  • PSM2
Epitope
AA 318-347, Center
15
13
8
3
2
1
Reactivity
Human, Mouse (Murine)
21
4
Host
Rabbit
21
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
18
15
15
14
2
1
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Immunogen This MCAF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-347 AA from the Central region of human MCAF2.
Clone RB28618
Isotype Ig
Specificity This MCAF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-355 amino acids from the Central region of human MCAF2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name MCAF2 (ATF7IP2 Antibody Abstract)
Background Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone 'Lys-9' trimethylation activity (Probable).
Synonyms: ATF7IP2,Activating transcription factor 7-interacting protein 2,MCAF2
Molecular Weight 75764 DA
Gene ID 80063
NCBI Accession NP_079273
UniProt Q5U623
Research Area Translation Factors, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Signaling, Cell Structure
Pathways
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Activating Transcription Factor 7 Interacting Protein 2 (ATF7IP2) (AA 318-347), (Center) antibody (ABIN654466) MCAF2 Antibody (Center) western blot analysis in mouse stomach tissue lysates (35ug...
Western Blotting (WB) image for anti-Activating Transcription Factor 7 Interacting Protein 2 (ATF7IP2) (AA 318-347), (Center) antibody (ABIN654466) MCAF2 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane)....
Immunohistochemistry (IHC) image for anti-Activating Transcription Factor 7 Interacting Protein 2 (ATF7IP2) (AA 318-347), (Center) antibody (ABIN654466) MCAF2 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin...
Flow Cytometry (FACS) image for anti-Activating Transcription Factor 7 Interacting Protein 2 (ATF7IP2) (AA 318-347), (Center) antibody (ABIN654466) MCAF2 Antibody (Center) flow cytometric analysis of CEM cells (right histogram) comp...
Background publications Ichimura, Watanabe, Sakamoto et al.: "Transcriptional repression and heterochromatin formation by MBD1 and MCAF/AM family proteins." in: The Journal of biological chemistry, Vol. 280, Issue 14, pp. 13928-35, 2005 (PubMed).