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Details for Product No. ABIN654466

Activating Transcription Factor 7 Interacting Protein 2 (ATF7IP2) (AA 318-347), (Center) antibody

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Synonyms MCAF2, 4930558K11Rik, BC018510, Get-1, PSM2
»Alternatives AA 318-347, Center
»Alternatives Human, Mouse (Murine)
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
Pubmed 1 reference available
Catalog no. ABIN654466
Quantity 400 µL
291.50 $   Plus shipping costs $45.00
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Immunogen This MCAF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-347 AA from the Central region of human MCAF2.
Clone RB28618
Isotype Ig
Specificity This MCAF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-355 amino acids from the Central region of human MCAF2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name MCAF2
Background Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone 'Lys-9' trimethylation activity (Probable).
Synonyms: ATF7IP2,Activating transcription factor 7-interacting protein 2,MCAF2
Molecular Weight 75764 DA
Gene ID 80063
UniProt Q5U623, NP_079273.2
Research Area Translation Factors, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Signaling, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Ichimura, Watanabe, Sakamoto et al.: "Transcriptional repression and heterochromatin formation by MBD1 and MCAF/AM family proteins." in: The Journal of biological chemistry, Vol. 280, Issue 14, pp. 13928-35, 2005 (PubMed).

Alternatives for antigen "Activating Transcription Factor 7 Interacting Protein 2 (ATF7IP2)", type "Antibodies"
Hosts (5)
Reactivities (5), (3)
Applications (5), (3), (2), (2), (1)
Epitopes (2), (2), (1), (1), (1)