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ATF7IP2 antibody (N-Term)

ATF7IP2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2790606
  • Target See all ATF7IP2 Antibodies
    ATF7IP2 (Activating Transcription Factor 7 Interacting Protein 2 (ATF7IP2))
    Binding Specificity
    • 7
    • 7
    • 6
    • 6
    • 1
    • 1
    N-Term
    Reactivity
    • 17
    • 8
    Human
    Host
    • 17
    Rabbit
    Clonality
    • 17
    Polyclonal
    Conjugate
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    This ATF7IP2 antibody is un-conjugated
    Application
    • 16
    • 13
    • 12
    • 12
    • 4
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    EEIVHSETKL EQVVCSYQKP SRTTESPSRV FTEEAKDSLN TSENDSEHQT
    Predicted Reactivity
    Human: 100%
    Characteristics
    This is a rabbit polyclonal antibody against ATF7IP2. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human ATF7IP2
    Top Product
    Discover our top product ATF7IP2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 543 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    ATF7IP2 (Activating Transcription Factor 7 Interacting Protein 2 (ATF7IP2))
    Alternative Name
    ATF7IP2 (ATF7IP2 Products)
    Synonyms
    MCAF2 antibody, 4930558K11Rik antibody, BC018510 antibody, Get-1 antibody, PSM2 antibody, activating transcription factor 7 interacting protein 2 antibody, ATF7IP2 antibody, Atf7ip2 antibody
    Background
    ATF7IP2 is a recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. It can both act as an activator or a repressor depending on the context. ATF7IP2 mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity.
    Alias Symbols: FLJ12668, MCAF2
    Protein Interaction Partner: SETDB1, SP1, MBD1,
    Protein Size: 543
    Molecular Weight
    59 kDa
    Gene ID
    80063
    NCBI Accession
    NM_001256160, NP_001243089
    UniProt
    Q5U623
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