Sel-1 Suppressor of Lin-12-Like (C. Elegans) (SEL1L) (AA 156-182), (Center) antibody

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Antigen
Synonyms PRO1063, SEL1-LIKE, SEL1L1, AW493766, Sel1h, mKIAA4137, SEL1L, MGC99195
Epitope
AA 156-182, Center
(3), (3), (2), (2), (2), (1)
Reactivity
Human
(22), (13), (13), (12), (12), (2)
Host
Rabbit
(18), (5), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
(14), (10), (9), (6), (2), (1), (1)
Pubmed 2 references available
Catalog no. ABIN654642
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This SEL1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-182 AA from the Central region of human SEL1L.
Clone RB28451
Isotype Ig
Specificity This SEL1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-186 amino acids from the Central region of human SEL1L.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name SEL1L
Background May play a role in Notch signaling (By similarity). May be involved in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins.
Synonyms: Protein sel-1 homolog 1,SEL1L,TSA305
Molecular Weight 88755 DA
Gene ID 6400
UniProt Q9UBV2, NP_005056.3
Research Area Cell Signaling, Protein Modifications, Cell Structure
Application Notes WB = 1:1000, IHC = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Sel-1 Suppressor of Lin-12-Like (C. Elegans) (SEL1L) (AA 156-182), (Center) antibody SEL1L Antibody (Center) (ABIN654642) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications Cormier, Tamura, Sunryd et al.: "EDEM1 recognition and delivery of misfolded proteins to the SEL1L-containing ERAD complex." in: Molecular cell, Vol. 34, Issue 5, pp. 627-33, 2009 (PubMed).

Riemer, Appenzeller-Herzog, Johansson et al.: "A luminal flavoprotein in endoplasmic reticulum-associated degradation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 35, pp. 14831-6, 2009 (PubMed).

Hosts (18), (5), (1)
Reactivities (22), (13), (13), (12), (12), (2)
Applications (14), (10), (9), (6), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (3), (3), (2), (2), (2), (1)
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