SEL1L antibody (AA 22-181) (HRP)

Catalog No. ABIN7166105

Product Details anti-SEL1L Antibody (HRP)

Target: SEL1L (SEL1L adaptor subunit of ERAD E3 ubiquitin ligase (SEL1L))

Binding Specificity: AA 22-181

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEL1L antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Protein sel-1 homolog 1 protein (22-181AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SEL1L

Target: SEL1L (SEL1L adaptor subunit of ERAD E3 ubiquitin ligase (SEL1L))

Alternative Name: SEL1L (SEL1L Products)

Synonyms: PRO1063 antibody, SEL1-LIKE antibody, SEL1L1 antibody, AW493766 antibody, Sel1h antibody, mKIAA4137 antibody, SEL1L antibody, MGC99195 antibody, Sel-1L antibody, SEL1L ERAD E3 ligase adaptor subunit antibody, sel-1 suppressor of lin-12-like (C. elegans) antibody, sel-1 suppressor of lin-12-like L homeolog antibody, sel-1 suppressor of lin-12-like antibody, SEL1L antibody, Sel1l antibody, sel1l.L antibody, sel1l antibody

Background:

Background: Plays a role in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (PubMed:16186509). Enhances SYVN1 stability. Plays a role in LPL maturation and secretion. Required for normal differentiation of the pancreas epithelium, and for normal exocrine function and survival of pancreatic cells. May play a role in Notch signaling.

Aliases: IBD2 antibody, PRO1063 antibody, Protein sel-1 homolog 1 antibody, SE1L1_HUMAN antibody, Sel 1 like protein antibody, Sel 1 suppressor of lin 12 like antibody, Sel-1L antibody, SEL1 LIKE antibody, Sel1l antibody, SEL1LIKE antibody, Suppressor of lin-12-like protein 1 antibody, TSA305 antibody, UNQ128 antibody, UNQ128/PRO1063 antibody

UniProt: Q9UBV2